ArticlePlant biotechnology journal2016
Improving nutritional quality and fungal tolerance in soya bean and grass pea by expressing an oxalate decarboxylase.
Article in Plant biotechnology journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 68 citations in OpenAlex.
- Plant-derived vesicle-like nanoparticles in food crops: emerging insights into nutritional biofortification and biomedical applications.Plant biotechnology journal · 2025Review
- Industrial Production of Functional Foods for Human Health and Sustainability.Foods (Basel, Switzerland) · 2024Review
- Optimization of Plant Oxalate Quantification and Generation of Low-Oxalate Maize (Plants (Basel, Switzerland) · 2024Article
- Nitrogen reduces calcium availability by promoting oxalate biosynthesis in apple leaves.Horticulture research · 2024Article
- Role of oxalic acid in fungal and bacterial metabolism and its biotechnological potential.World journal of microbiology & biotechnology · 2024Review
- Oxalate and oxalotrophy: an environmental perspective.Sustainable microbiology · 2024Review
- Genome Editing and Protein Energy Malnutrition.Advances in experimental medicine and biology · 2023Article
- Identification and characterization of the key enzyme in the biosynthesis of the neurotoxin β-ODAP in grass pea.The Journal of biological chemistry · 2022Article
- The identification and characterization of an oxalyl-CoA synthetase from grass pea (RSC chemical biology · 2022Article
- N-Acetylglucosamine Sensing and Metabolic Engineering for Attenuating Human and Plant Pathogens.Bioengineering (Basel, Switzerland) · 2022Review
- Genetic manipulation of anti-nutritional factors in major crops for a sustainable diet in future.Frontiers in plant science · 2022Review
- The Tomato Transcription Factor SlNAC063 Is Required for Aluminum Tolerance by RegulatingFrontiers in plant science · 2022Article
- Tomato Oxalyl-CoA Synthetase Degrades Oxalate and Affects Fruit Quality.Frontiers in plant science · 2022Article
- WRKY genes provide novel insights into their role againstFrontiers in plant science · 2022Article
- An Arabidopsis Oxalyl-CoA Decarboxylase, AtOXC, Is Important for Oxalate Catabolism in Plants.International journal of molecular sciences · 2021Article
- Current Perspectives on Reducing the β-ODAP Content and Improving Potential Agronomic Traits in Grass Pea (Frontiers in plant science · 2021Review
- Overexpression of the chitinase gene CmCH1 from Coniothyrium minitans renders enhanced resistance to Sclerotinia sclerotiorum in soybean.Transgenic research · 2020Article
- Review
- Mechanisms of plant protection against two oxalate-producing fungal pathogens by oxalotrophic strains of Stenotrophomonas spp.Plant molecular biology · 2019Article
- Enhanced resistance to sclerotinia stem rot in transgenic soybean that overexpresses a wheat oxalate oxidase.Transgenic research · 2019Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Soya bean (Glycine max) and grass pea (Lathyrus sativus) seeds are important sources of dietary proteins; however, they also contain antinutritional metabolite oxalic acid (OA). Excess dietary intake of OA leads to nephrolithiasis due to the formation of calcium oxalate crystals in kidneys. Besides, OA is also a known precursor of β-N-oxalyl-L-α,β-diaminopropionic acid (β-ODAP), a neurotoxin found in grass pea. Here, we report the reduction in OA level in soya bean (up to 73%) and grass pea (up to 75%) seeds by constitutive and/or seed-specific expression of an oxalate-degrading enzyme, oxalate decarboxylase (FvOXDC) of Flammulina velutipes. In addition, β-ODAP level of grass pea seeds was also reduced up to 73%. Reduced OA content was interrelated with the associated increase in seeds micronutrients such as calcium, iron and zinc. Moreover, constitutive expression of FvOXDC led to improved tolerance to the fungal pathogen Sclerotinia sclerotiorum that requires OA during host colonization. Importantly, FvOXDC-expressing soya bean and grass pea plants were similar to the wild type with respect to the morphology and photosynthetic rates, and seed protein pool remained unaltered as revealed by the comparative proteomic analysis. Taken together, these results demonstrated improved seed quality and tolerance to the fungal pathogen in two important legume crops, by the expression of an oxalate-degrading enzyme.
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