ArticleStructural dynamics (Melville, N.Y.)2014
Active and silent chromophore isoforms for phytochrome Pr photoisomerization: An alternative evolutionary strategy to optimize photoreaction quantum yields.
Article in Structural dynamics (Melville, N.Y.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed.
- Polarization-resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume.FEBS open bio · 2026Article
- Photoisomerization of phytochrome's chromophore: a vibrational spectroscopic view on the primary ground state processes.RSC advances · 2025Article
- Chemical Mechanism of Allosteric and Asymmetric Dark Reversion in a Bacterial Phytochrome Uncovered by Cryo-EM.Journal of the American Chemical Society · 2025Article
- Ultrafast, remote-controlled protonation reaction enables structural changes in a phytochrome.Science advances · 2025Article
- Pr and Pfr structures of plant phytochrome A.Nature communications · 2025Article
- Integrated Study of Fluorescence Enhancement in the Y176H Variant of Cyanobacterial Phytochrome Cph1.Biochemistry · 2025Article
- The structural effect between the output module and chromophore-binding domain is a two-way street via the hairpin extension.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2022Article
- Ultrafast proton-coupled isomerization in the phototransformation of phytochrome.Nature chemistry · 2022Article
- Core and rod structures of a thermophilic cyanobacterial light-harvesting phycobilisome.Nature communications · 2022Article
- Improved fluorescent phytochromes for in situ imaging.Scientific reports · 2022Article
- Ultrafast Photoconversion Dynamics of the Knotless PhytochromeInternational journal of molecular sciences · 2021Article
- Effect of the PHY Domain on the Photoisomerization Step of the Forward PChemistry (Weinheim an der Bergstrasse, Germany) · 2020Article
- The Origin of Ultrafast Multiphasic Dynamics in Photoisomerization of Bacteriophytochrome.The journal of physical chemistry letters · 2020Article
- The interplay between chromophore and protein determines the extended excited state dynamics in a single-domain phytochrome.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- QM/MM Benchmarking of Cyanobacteriochrome Slr1393g3 Absorption Spectra.Molecules (Basel, Switzerland) · 2019Article
- Protonation Heterogeneity Modulates the Ultrafast Photocycle Initiation Dynamics of Phytochrome Cph1.The journal of physical chemistry letters · 2018Article
- 3D Structures of Plant Phytochrome A as Pr and Pfr From Solid-State NMR: Implications for Molecular Function.Frontiers in plant science · 2018Article
- Ultrafast electronic and vibrational dynamics in brominated aluminum corroles: Energy relaxation and triplet formation.Structural dynamics (Melville, N.Y.) · 2016Article
- Fast Photochemistry of Prototypical Phytochromes-A Species vs. Subunit Specific Comparison.Frontiers in molecular biosciences · 2015Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Photoisomerization of a protein bound chromophore is the basis of light sensing of many photoreceptors. We tracked Z-to-E photoisomerization of Cph1 phytochrome chromophore PCB in the Pr form in real-time. Two different phycocyanobilin (PCB) ground state geometries with different ring D orientations have been identified. The pre-twisted and hydrogen bonded PCB(a) geometry exhibits a time constant of 30 ps and a quantum yield of photoproduct formation of 29%, about six times slower and ten times higher than that for the non-hydrogen bonded PCB(b) geometry. This new mechanism of pre-twisting the chromophore by protein-cofactor interaction optimizes yields of slow photoreactions and provides a scaffold for photoreceptor engineering.
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Registered trials
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