ReviewJournal of immunology research2015
RNAi and Antiviral Defense in the Honey Bee.
Review in Journal of immunology research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 1 synthesis or guideline pooled it, 87 citations in OpenAlex.
- Meta-analysis of honey bee neurogenomic response links Deformed wing virus type A to precocious behavioral maturation.Scientific reports · 2020Pooled it
- Experimental infection of acute bee paralysis virus induces differential responses of selected honey bee immune genes, independent of varroa resistance.Scientific reports · 2026Article
- Insight into the Prospects of RNA Interference for Honey Bee Pathogens and Parasite Control.Insects · 2026Review
- Review
- Longevity and foraging performance of honey bees treated with an RNAi-based Varroa destructor biopesticide.Scientific reports · 2026Article
- Neurotranscriptomic profiling of deformed wing virus-infected honey bee foragers (Apis mellifera) with different cognitive abilities.Biology open · 2025Article
- Epigenetic Mechanisms inCurrent issues in molecular biology · 2025Review
- Article
- The eusocial non-code: Unveiling the impact of noncoding RNAs on Hymenoptera eusocial evolution.Non-coding RNA research · 2025Review
- A miR-JL-5 inhibitor modulates the proliferation ofFrontiers in insect science · 2025Article
- DsRNA as pathogen-associated molecular pattern in innate immunity and multiple functions of the RNAi machinery complicate the use of RNAi in pest control.Frontiers in insect science · 2025Review
- Acute bee paralysis virus regulation of microRNA expression dynamics in the insect host (Frontiers in cellular and infection microbiology · 2025Article
- Liposome-based RNAi delivery in honeybee for inhibiting parasiteSynthetic and systems biotechnology · 2024Article
- Mechanisms of Pathogen and Pesticide Resistance in Honey Bees.Physiology (Bethesda, Md.) · 2024Review
- Identification of ecdysone receptor target genes in the worker honey bee brains during foraging behavior.Scientific reports · 2023Article
- Potassium ion channels as a molecular target to reduce virus infection and mortality of honey bee colonies.Virology journal · 2023Article
- Large-Scale Application of Double-Stranded RNA Shows Potential for Reduction of Sacbrood Virus Disease inViruses · 2023Article
- AmAtg2B-Mediated Lipophagy Regulates Lipolysis of Pupae inInternational journal of molecular sciences · 2023Article
- Age-related response to mite parasitization and viral infection in the honey bee suggests a trade-off between growth and immunity.PloS one · 2023Article
- Dietary Supplement of Grape Wastes Enhances Honeybee Immune System and Reduces Deformed Wing Virus (DWV) Load.Antioxidants (Basel, Switzerland) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Honey bees play an important agricultural and ecological role as pollinators of numerous agricultural crops and other plant species. Therefore, investigating the factors associated with high annual losses of honey bee colonies in the US is an important and active area of research. Pathogen incidence and abundance correlate with Colony Collapse Disorder- (CCD-) affected colonies in the US and colony losses in the US and in some European countries. Honey bees are readily infected by single-stranded positive sense RNA viruses. Largely dependent on the host immune response, virus infections can either remain asymptomatic or result in deformities, paralysis, or death of adults or larvae. RNA interference (RNAi) is an important antiviral defense mechanism in insects, including honey bees. Herein, we review the role of RNAi in honey bee antiviral defense and highlight some parallels between insect and mammalian immune systems. A more thorough understanding of the role of pathogens on honey bee health and the immune mechanisms bees utilize to combat infectious agents may lead to the development of strategies that enhance honey bee health and result in the discovery of additional mechanisms of immunity in metazoans.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.