Evidence map›Paper›PMID 26798637›Full record

ReviewBioMed research international2015

The Effect of Perioperative Ischemia and Reperfusion on Multiorgan Dysfunction following Abdominal Aortic Aneurysm Repair.

Konstantina Katseni, Athanasios Chalkias, Thomas Kotsis, Nikolaos Dafnios, Vassilis Arapoglou, Georgios Kaparos, Emmanuel Logothetis, Nicoletta Iacovidou, Eleni Karvouni, Konstantinos Katsenis

Registry-linked trialOpen access · hybridAbstract readReview
In one paragraph

Review in BioMed research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04630535 (Obstructive Sleep Apnea as a Remote Ischemic Preconditioning in Patients Scheduled for Aorto-bifemoral Bypass Surgery), which is not on this map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04630535 recruitingnot on this mapstarted 2020, after this paper: background citation

Obstructive Sleep Apnea as a Remote Ischemic Preconditioning in Patients Scheduled for Aorto-bifemoral Bypass Surgery

TypeobservationalSponsorSt. Anne's University Hospital Brno, Czech RepublicRan2020 to 2029Enrolled100ConditionsObstructive Sleep Apnea, Vascular Aneurysm, Ischemia Reperfusion InjuryArmsaorto-bifemoral bypass surgery
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 38 citations in OpenAlex.

  1. Trial
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  8. Aortic ischemia-reperfusion injury and potency of fluoxetine.Iranian journal of basic medical sciences · 2023
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  15. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Konstantina KatseniVascular Surgery Unit, 2nd Surgical Department, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Athanasios ChalkiasMSc "Cardiopulmonary Resuscitation", Medical School, National and Kapodistrian University of Athens, Athens, Greece; Hellenic Society of Cardiopulmonary Resuscitation, Athens, Greece; Department of Anesthesiology, Tzaneio Hospital of Piraeus, Piraeus, Greece.ORCID 0000-0002-7634-4665
Thomas KotsisVascular Surgery Unit, 2nd Surgical Department, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Nikolaos DafniosVascular Surgery Unit, 2nd Surgical Department, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Vassilis ArapoglouVascular Surgery Unit, 2nd Surgical Department, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Georgios KaparosDepartment of Biopathology, Aretaion Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Emmanuel LogothetisDepartment of Biopathology, Aretaion Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Nicoletta IacovidouHellenic Society of Cardiopulmonary Resuscitation, Athens, Greece; Neonatal Division, Department of Pediatrics, Aretaion Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.ORCID 0000-0001-8021-6191
Eleni KarvouniDepartment of Biopathology, Aretaion Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Konstantinos KatsenisVascular Surgery Unit, 2nd Surgical Department, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
National and Kapodistrian University of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Abdominal aortic aneurysms (AAAs) are relatively common and are potentially life-threatening medical problems. The aim of this review is to provide an overview of the effect of I/R injury on multiorgan failure following AAA repair. The PubMed, CINAHL, EMBASE, Medline, Cochrane Review, and Scopus databases were comprehensively searched for articles concerning the pathophysiology of I/R and its systemic effects. Cross-referencing was performed using the bibliographies from the articles obtained. Articles retrieved were restricted to those published in English. One of the most prominent characteristics of AAA open repair is the double physiological phenomenon of ischemia-reperfusion (I/R) that happens either at the time of clamping or following the aortic clamp removal. Ischemia-reperfusion injury causes significant pathophysiological disturbances to distant organs, increasing the possibility for postoperative multiorgan failure. Although tissue injury is mediated by diverse mechanisms, microvascular dysfunction seems to be the final outcome of I/R.

Indexed as

Multiple Organ FailurePostoperative ComplicationsReperfusion InjuryAnimalsAortic Aneurysm, AbdominalHumans

Identifiers

PMID26798637
PMCPMC4698535
OpenAlexW2206642544

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.