Evidence map›Paper›PMID 26798470›Full record

ArticleClinical kidney journal2016

Multimodal treatment of calcific uraemic arteriolopathy (calciphylaxis): a case series.

Domenico Russo, Alfredo Capuano, Mario Cozzolino, Paola Napolitano, Francesca Mosella, Luigi Russo, Caterina Saviano, Carmine Zoccali

Abstract read
In one paragraph

Article in Clinical kidney journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
  4. Sodium Thiosulfate as a Treatment for Calciphylaxis.The Journal of clinical and aesthetic dermatology · 2021
    Article
  5. Article
  6. Article
  7. Article
  8. Calciphylaxis.Current opinion in nephrology and hypertension · 2017
    Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Domenico RussoDepartment of Nephrology , University of Naples , Napoli , Italy.
Alfredo CapuanoDepartment of Nephrology , University of Naples , Napoli , Italy.
Mario CozzolinoDepartment Nephrology , San Paolo Hospital , Milan , Italy.
Paola NapolitanoDepartment of Nephrology , University of Naples , Napoli , Italy.
Francesca MosellaDepartment of Surgery , University of Naples , Napoli , Italy.
Luigi RussoDepartment of Nephrology , Second University of Naples , Napoli , Italy.
Caterina SavianoDepartment of Internal Medicine , 'San Sebastiano' Hospital , Caserta , Italy.
Carmine ZoccaliClinical Epidemiology and Pathophysiology of Renal Diseases and Hypertension, Reggio Calabria Unit of CNR-IFC (National Research Council of Italy and Institute of Clinical Physiology), Reggio Calabria, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis is an incident series of five dialysis patients with late-diagnosed calcific uraemic arteriolophathy (CUA), severe uncontrolled hyperparathyroidism and infected skin ulcerations.

methodsA multimodal intervention was based on wound care, antibiotics, surgical debridement, sodium thiosulphate and cinacalcet and associated with regression of skin disease in four cases after varying treatment time periods ranging from 4 to 33 months.

resultsMultimodal treatment including sodium thiosulphate and cinacalcet was associated with very favourable local outcomes and survival. This series further confirms that the diagnosis of CUA is rarely made at the nodular, non-ulcerative phase of the disease.

conclusionsThis series contributes to the build-up of case series reporting on the treatment of CUA, and will hopefully serve as a basis of well-conceived comparative effectiveness studies investigating the value of the combined interventions applied so far in this severe condition.

Indexed as

calcific uraemic arteriolopathycinacalcetCUAparathyroid hormoneskin ulcers

Identifiers

PMID26798470
PMCPMC4720199

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.