Evidence map›Paper›PMID 26798459›Full record

ReviewClinical kidney journal2016

Focus on renal congestion in heart failure.

Baris Afsar, Alberto Ortiz, Adrian Covic, Yalcin Solak, David Goldsmith, Mehmet Kanbay

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Clinical kidney journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06463964 (Predictors of Acute Kidney Injury in Patients With Acute Decompensated Heart Failure in Emergency), which is not on this map. Cited by 65 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06463964 unknown statusnot on this mapstarted 2024, after this paper: background citation

Predictors of Acute Kidney Injury in Patients With Acute Decompensated Heart Failure in Emergency

TypeobservationalSponsorSohag UniversityRan2024 to 2024Enrolled100ConditionsAcute Kidney Injury, Acute Heart FailureArmsSerum Creatinine
3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 1 synthesis or guideline pooled it, 101 citations in OpenAlex.

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  20. Sodium glucose cotransporter 2 inhibitor as a promising therapy for congestive kidney injury.Hypertension research : official journal of the Japanese Society of Hypertension · 2024
    Article

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 4 countries.

Baris AfsarDepartment of Medicine, Division of Nephrology , Konya Numune State Hospital , Konya , Turkey.
Alberto OrtizNephrology and Hypertension Department , IIS-Fundacion Jimenez Diaz and School of Medicine , Madrid , Spain.
Adrian CovicNephrology Clinic, Dialysis and Renal Transplant Center , 'C.I. PARHON' University Hospital, and 'Grigore T. Popa' University of Medicine , Iasi , Romania.
Yalcin SolakDepartment of Nephrology , Sakarya Training and Research Hospital , Sakarya , Turkey.
David GoldsmithRenal and Transplantation Department , Guy's and St Thomas' Hospitals , London , UK.
Mehmet KanbayDepartment of Medicine, Division of Nephrology , Koc University School of Medicine , Istanbul , Turkey.
Grigore T. Popa University of Medicine and Pharmacy · ROHospital Universitario Fundación Jiménez Díaz · ESKoç University · TRKonya Numune Hastanesi · TRSakarya Eğitim ve Araştırma Hastanesi · TRSt Thomas' Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hospitalizations due to heart failure are increasing steadily despite advances in medicine. Patients hospitalized for worsening heart failure have high mortality in hospital and within the months following discharge. Kidney dysfunction is associated with adverse outcomes in heart failure patients. Recent evidence suggests that both deterioration in kidney function and renal congestion are important prognostic factors in heart failure. Kidney congestion in heart failure results from low cardiac output (forward failure), tubuloglomerular feedback, increased intra-abdominal pressure or increased venous pressure. Regardless of the cause, renal congestion is associated with increased morbidity and mortality in heart failure. The impact on outcomes of renal decongestion strategies that do not compromise renal function should be explored in heart failure. These studies require novel diagnostic markers that identify early renal damage and renal congestion and allow monitoring of treatment responses in order to avoid severe worsening of renal function. In addition, there is an unmet need regarding evidence-based therapeutic management of renal congestion and worsening renal function. In the present review, we summarize the mechanisms, diagnosis, outcomes, prognostic markers and treatment options of renal congestion in heart failure.

Indexed as

acute kidney injuryfluid managementheart failurehypervolemiarenal congestion

Identifiers

PMID26798459
PMCPMC4720202
OpenAlexW2186245350

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.