Evidence map›Paper›PMID 26798381›Full record

ArticleKorean circulation journal2016

Neutrophil to Lymphocyte Ratio Predicts Left Ventricular Remodeling in Patients with ST Elevation Myocardial Infarction after Primary Percutaneous Coronary Intervention.

Abdurrezzak Börekçi, Mustafa Gür, Caner Türkoğlu, Ahmet Oytun Baykan, Taner Şeker, Durmuş Yıldıray Şahin, Hazar Harbalıoğlu, Zafer Elbasan, Mustafa Topuz, Murat Çaylı

Open access · hybridAbstract read
In one paragraph

Article in Korean circulation journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
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  10. Observational
  11. Article
  12. The Role of Inflammation in Cardiovascular Outcome.Current atherosclerosis reports · 2017
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Abdurrezzak BörekçiDepartment of Cardiology, School of Medicine, Kafkas University, Kars, Turkey.
Mustafa GürDepartment of Cardiology, School of Medicine, Kafkas University, Kars, Turkey.
Caner TürkoğluDepartment of Cardiology, Yenimahalle State Hospital, Ankara, Turkey.
Ahmet Oytun BaykanDepartment of Cardiology, Adana Numune Training and Research Hospital, Adana, Turkey.
Taner ŞekerDepartment of Cardiology, Adana Numune Training and Research Hospital, Adana, Turkey.
Durmuş Yıldıray ŞahinDepartment of Cardiology, Adana Numune Training and Research Hospital, Adana, Turkey.
Hazar HarbalıoğluDepartment of Cardiology, Adana Numune Training and Research Hospital, Adana, Turkey.
Zafer ElbasanDepartment of Cardiology, Adana Numune Training and Research Hospital, Adana, Turkey.
Mustafa TopuzDepartment of Cardiology, Adana Numune Training and Research Hospital, Adana, Turkey.
Murat ÇaylıDepartment of Cardiology, School of Medicine, Dicle University, Diyarbakır, Turkey.
Kafkas University · TRDicle University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesIt has been demonstrated that the neutrophil/lymphocyte ratio (NLR) might be a useful marker to predict cardiovascular risk and events. We aimed to investigate the role of the NLR to predict ventricular remodeling (VR) in patients with anterior ST-elevation myocardial infarction (STEMI) who were treated with primary percutaneous coronary intervention. SUBJECTS AND

methodsWe prospectively included 274 consecutive anterior STEMI patients. Echocardiography was performed during admission and at six months after myocardial infarction. VR was defined as at least 20% increase from baseline in left ventricular end-diastolic volume. Patients were divided into two groups according to their VR status: VR (n=67) and non-VR (n=207). Total and differential leukocyte count, N-terminal pro-brain natriuretic peptide (NT-proBNP) and other biochemical markers were measured at admission and 24 hours later.

resultsCompared with the non-VR group, peak creatine kinase MB (CK-MB), NT-proBNP (24 h), neutrophil/lymphocyte ratio, presence of diabetes, no-reflow frequency and wall motion score index were significantly higher in patients with VR (p<0.05 for all). On multivariate logistic regression analysis, NLR (β=2.000, 95% confidence interval=1.577-2.537, p<0.001) as well as peak CK-MB, NT-proBNP (24 h), WMSI and diabetes incidence were associated with VR. The cutoff value of the neutrophil/lymphocyte ratio obtained by receiver operator characteristic curve analysis was 4.25 for the prediction of VR (sensitivity: 79 %, specificity: 74%).

conclusionIn patients with anterior STEMI, initial NLR and NT-proBNP measured 24 hours after admission may be useful for predicting adverse cardiovascular events including left VR.

Indexed as

BNPMyocardial infarctionNeutrophils, lymphocytesNo-reflowRemodeling

Identifiers

PMID26798381
PMCPMC4720845
OpenAlexW2258696789

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.