ReviewMolecular neurobiology
Activity-dependent regulation of gene expression in muscle and neuronal cells.
Review in Molecular neurobiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
26 citing papers in PubMed, 133 citations in OpenAlex.
- HDAC6 regulates microtubule stability and clustering of AChRs at neuromuscular junctions.The Journal of cell biology · 2020Article
- Functional characterization of alpha9-containing cholinergic nicotinic receptors in the rat adrenal medulla: implication in stress-induced functional plasticity.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2010Article
- Regulation of acetylcholine receptor gene expression in human myasthenia gravis muscles. Evidences for a compensatory mechanism triggered by receptor loss.The Journal of clinical investigation · 1998Article
- Implication of a multisubunit Ets-related transcription factor in synaptic expression of the nicotinic acetylcholine receptor.The EMBO journal · 1998Article
- Release of acetylcholine from embryonic myocytes in Xenopus cell cultures.The Journal of physiology · 1998Article
- mRNAs coding for neurotransmitter receptors and voltage-gated sodium channels in the adult rabbit visual cortex after monocular deafferentiation.Proceedings of the National Academy of Sciences of the United States of America · 1998Article
- Regulation of quantal secretion from developing motoneurons by postsynaptic activity-dependent release of NT-3.The Journal of neuroscience : the official journal of the Society for Neuroscience · 1997Article
- ARIA/HRG regulates AChR epsilon subunit gene expression at the neuromuscular synapse via activation of phosphatidylinositol 3-kinase and Ras/MAPK pathway.The Journal of cell biology · 1996Article
- The transcriptional regulation of the preproenkephalin gene.The Biochemical journal · 1995Review
- AML1 is expressed in skeletal muscle and is regulated by innervation.Molecular and cellular biology · 1994Article
- Transgenic engineering of neuromuscular junctions in Xenopus laevis embryos transiently overexpressing key cholinergic proteins.Proceedings of the National Academy of Sciences of the United States of America · 1994Article
- Nicotine-related brain disorders: the neurobiological basis of nicotine dependence.Cellular and molecular neurobiology · 1994Review
- Role of muscle insulin-like growth factors in nerve sprouting: suppression of terminal sprouting in paralyzed muscle by IGF-binding protein 4.The Journal of cell biology · 1994Article
- An E box mediates activation and repression of the acetylcholine receptor delta-subunit gene during myogenesis.Molecular and cellular biology · 1993Article
- Presumptive Renshaw cells contain decreased calbindin during recovery from sciatic nerve lesions.Proceedings of the National Academy of Sciences of the United States of America · 1993Article
- Electrical activity-dependent regulation of the acetylcholine receptor delta-subunit gene, MyoD, and myogenin in primary myotubes.Proceedings of the National Academy of Sciences of the United States of America · 1993Article
- Nicotinic receptor-associated 43K protein and progressive stabilization of the postsynaptic membrane.Molecular neurobiology · 1992Review
- Functional adult acetylcholine receptor develops independently of motor innervation in Sol 8 mouse muscle cell line.The EMBO journal · 1991Article
- Neural factors regulate AChR subunit mRNAs at rat neuromuscular synapses.The Journal of cell biology · 1991Article
- An acetylcholine receptor alpha-subunit promoter conferring preferential synaptic expression in muscle of transgenic mice.The EMBO journal · 1991Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In both the central and the peripheral nervous systems, impulse activity regulates the expression of a vast number of genes that code for synaptic proteins, including neuropeptides, enzymes involved in neurotransmitter biosynthesis and degradation, and membrane receptors. In recent years, the mechanisms involved in these regulations became amenable to investigation by the methods of recombinant DNA technology. The first part of this review focuses on the activity-dependent control of nicotinic acetylcholine receptor biosynthesis in vertebrate muscle, a model case for the regulation of synaptic protein biosynthesis at the postsynaptic level. The second part summarizes some examples of neuronal proteins whose biosynthesis is under the control of transsynaptic impulse activity. The first, second, and third intracellular messengers involved in membrane-to-gene signaling are discussed, as are possible posttranscriptional control mechanisms. Finally, models are proposed for a role of neuronal activity in the genesis and stabilization of the synapse.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.