ArticleJournal of comparative pathology2016
Myocarditis caused by Feline Immunodeficiency Virus in Five Cats with Hypertrophic Cardiomyopathy.
Article in Journal of comparative pathology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 39 citations in OpenAlex.
- Retrospective Evaluation of Anesthetic-Analgesic Protocols in Cats with and Without Transient Myocardial Thickening Following Gonadectomy.Animals : an open access journal from MDPI · 2026Article
- Arterial Thromboembolism in a Seven-Month-Old Cat with Acute Myocardial Injury.Animals : an open access journal from MDPI · 2026Article
- First Description of Hypertrophic Cardiomyopathy Phenotype in Apparently Healthy Cats in Morocco: An Echocardiographic Prevalence Study.Animals : an open access journal from MDPI · 2026Article
- Descriptive assessment of cardiac changes in cats with feline infectious peritonitis.Journal of veterinary internal medicine · 2026Article
- Transient Myocardial Thickening in an 11-Year-Old Cat Infected With Feline Infectious Peritonitis and Treated With GS-441524.Case reports in veterinary medicine · 2026Article
- Prevalence and characteristics of transient myocardial thickening in cats with hypertrophic cardiomyopathy phenotypes.The veterinary quarterly · 2025Article
- Myocarditis in Cats with Feline Infectious Peritonitis Can Be Cured with GS-441524 and Symptomatic Cardiovascular Treatment.Animals : an open access journal from MDPI · 2025Article
- Successful Management of Recurrent Pyothorax in a Cat: Clinical Findings with Medical and Surgical Approaches.Animals : an open access journal from MDPI · 2025Article
- The Pathological and Histopathological Findings in Cats with Clinically Recognised Hypertrophic Cardiomyopathy Are Related to the Severity of Clinical Signs and Disease Duration.Animals : an open access journal from MDPI · 2025Article
- Feline immunodeficiency virus: current insights into pathogenesis, clinical impact, and advances in treatment and vaccine development.Frontiers in veterinary science · 2025Review
- Case Report: Transient myocardial thickening in a cat secondary to acute cholangiohepatitis.Frontiers in veterinary science · 2025Article
- Case report: Diffuse large B-cell lymphoma presenting as congestive heart failure in a cat.Frontiers in veterinary science · 2024Article
- Long-term follow-up of a case of feline leishmaniosis treated with a combination of allopurinol and meglumine antimoniate.The Canadian veterinary journal = La revue veterinaire canadienne · 2023Article
- Clinical cases of infectious endocarditis in cats.Brazilian journal of veterinary medicine · 2022Article
- The Feline Cardiomyopathies: 3. Cardiomyopathies other than HCM.Journal of feline medicine and surgery · 2021Article
- Increased insulin-like growth factor 1 concentrations in a retrospective population of non-diabetic cats diagnosed with hypertrophic cardiomyopathy.Journal of feline medicine and surgery · 2021Article
- The correlation between cardiac and skeletal muscle pathology in animal models of idiopathic inflammatory myopathies.Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology · 2020Review
- Transient Myocardial Thickening in Cats Associated with Heart Failure.Journal of veterinary internal medicine · 2018Article
- Transient myocardial thickening associated with acute myocardial injury and congestive heart failure in twoJFMS open reportsArticle
- Article
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Viral infections have been implicated as the cause of cardiomyopathy in several mammalian species. This study describes hypertrophic cardiomyopathy (HCM) and myocarditis associated with feline immunodeficiency virus (FIV) infection in five cats aged between 1 and 4 years. Clinical manifestations included dyspnoea in four animals, one of which also exhibited restlessness. One animal showed only lethargy, anorexia and vomiting. Necropsy examination revealed marked cardiomegaly, marked left ventricular hypertrophy and pallor of the myocardium and epicardium in all animals. Microscopical and immunohistochemical examination showed multifocal infiltration of the myocardium with T lymphocytes and fewer macrophages, neutrophils and plasma cells. An intense immunoreaction for FIV antigen in the cytoplasm and nucleus of lymphocytes and the cytoplasm of some macrophages was observed via immunohistochemistry (IHC). IHC did not reveal the presence of antigen from feline calicivirus, coronavirus, feline leukaemia virus, feline parvovirus, Chlamydia spp. or Toxoplasma gondii. The results demonstrate the occurrence of FIV infection in inflammatory cells in the myocardium of five cats with myocarditis and HCM.
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