ArticleFunctional & integrative genomics2016
Transcriptome dynamics of a susceptible wheat upon Fusarium head blight reveals that molecular responses to Fusarium graminearum infection fit over the grain development processes.
Article in Functional & integrative genomics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 43 citations in OpenAlex.
- Molecular dissection of Xinong 511 spike rachis response to Fusarium head blight infection.Stress biology · 2025Article
- Comparative transcriptomic insights into molecular mechanisms of the susceptibility wheat variety MX169 response toMicrobiology spectrum · 2024Article
- Coronatine-Induced Maize Defense againstJournal of fungi (Basel, Switzerland) · 2023Article
- Boosting Immunity and Management against WheatPlants (Basel, Switzerland) · 2023Article
- Investigating the Resistance Mechanism of Wheat Varieties to Fusarium Head Blight Using Comparative Metabolomics.International journal of molecular sciences · 2023Article
- Comparative transcriptomics identifies the keyFrontiers in genetics · 2023Article
- Linking Multi-Omics to Wheat Resistance Types toInternational journal of molecular sciences · 2022Review
- Integrative Analysis of Genes Involved in the Global Response to Potato Wart Formation.Frontiers in plant science · 2022Article
- Multi-Omics Analysis Reveals a Regulatory Network of ZmCCT During Maize Resistance to Gibberella Stalk Rot at the Early Stage.Frontiers in plant science · 2022Article
- Comparative transcriptome analysis reveals distinct gene expression profiles in Brachypodium distachyon infected by two fungal pathogens.BMC plant biology · 2021Article
- A Comparative Transcriptome Analysis, Conserved Regulatory Elements and Associated Transcription Factors Related to Accumulation of Fusariotoxins in Grain of Rye (International journal of molecular sciences · 2020Article
- Searching for FHB Resistances in Bread Wheat: Susceptibility at the Crossroad.Frontiers in plant science · 2020Review
- Trichothecenes in Cereal Grains - An Update.Toxins · 2019Review
- A wheat NAC interacts with an orphan protein and enhances resistance to Fusarium head blight disease.Plant biotechnology journal · 2019Article
- Stable Isotope-Assisted Plant Metabolomics: Investigation of Phenylalanine-Related Metabolic Response in Wheat Upon Treatment With theFrontiers in plant science · 2019Article
- Unbalanced Roles of Fungal Aggressiveness and Host Cultivars in the Establishment of the Fusarium Head Blight in Bread Wheat.Frontiers in microbiology · 2019Article
- Genome Sequence of Fusarium graminearum Strain MDC_Fg1, Isolated from Bread Wheat Grown in France.Microbiology resource announcements · 2018Article
- A Review of the Interactions between Wheat and Wheat Pathogens: Zymoseptoria tritici, Fusarium spp. and Parastagonospora nodorum.International journal of molecular sciences · 2018Review
- Transcriptomics of cereal-Fusarium graminearum interactions: what we have learned so far.Molecular plant pathology · 2018Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In many plant/pathogen interactions, host susceptibility factors are key determinants of disease development promoting pathogen growth and spreading in plant tissues. In the Fusarium head blight (FHB) disease, the molecular basis of wheat susceptibility is still poorly understood while it could provide new insights into the understanding of the wheat/Fusarium graminearum (Fg) interaction and guide future breeding programs to produce cultivars with sustainable resistance. To identify the wheat grain candidate genes, a genome-wide gene expression profiling was performed in the French susceptible wheat cultivar, Recital. Gene-specific two-way ANOVA of about 40 K transcripts at five grain developmental stages identified 1309 differentially expressed genes. Out of these, 536 were impacted by the Fg effect alone. Most of these Fg-responsive genes belonged to biological and molecular functions related to biotic and abiotic stresses indicating the activation of common stress pathways during susceptibility response of wheat grain to FHB. This analysis revealed also 773 other genes displaying either specific Fg-responsive profiles along with grain development stages or synergistic adjustments with the grain development effect. These genes were involved in various molecular pathways including primary metabolism, cell death, and gene expression reprogramming. An increasingly complex host response was revealed, as was the impact of both Fg infection and grain ontogeny on the transcription of wheat genes. This analysis provides a wealth of candidate genes and pathways involved in susceptibility responses to FHB and depicts new clues to the understanding of the susceptibility determinism in plant/pathogen interactions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.