Evidence map›Paper›PMID 26797356›Full record

ArticleAJR. American journal of roentgenology2016

Appearance and Frequency of Gas Interface Artifacts Involving Small Bowel on Rapid-Voltage-Switching Dual-Energy CT Iodine-Density Images.

En-Haw Wu, So Yeon Kim, Z Jane Wang, Wei-Chou Chang, Li-Qin Zhao, Benjamin M Yeh

Abstract read
In one paragraph

Article in AJR. American journal of roentgenology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Oral CT Contrast Agents: What's New and Why, From theAJR. American journal of roentgenology · 2024
    Review
  3. Review
  4. Dual-energy CT in diffuse liver disease: is there a role?Abdominal radiology (New York) · 2020
    Review
  5. Article
  6. Dual-Energy CT Images: Pearls and Pitfalls.Radiographics : a review publication of the Radiological Society of North America, Inc
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

En-Haw Wu1 Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital, Linkou and Chang Gung University College of Medicine, Taoyuan County, Taiwan.
So Yeon Kim2 Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Z Jane Wang3 Department of Radiology and Biomedical Imaging, University of California San Francisco, 505 Parnassus Ave, San Francisco, CA 94143-0628.
Wei-Chou Chang4 Tri-Service General Hospital and National Defense Medical Center, Taipei, Taiwan.
Li-Qin Zhao5 Department of Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Benjamin M Yeh3 Department of Radiology and Biomedical Imaging, University of California San Francisco, 505 Parnassus Ave, San Francisco, CA 94143-0628.

Funding

Nanoparticle CT Contrast Agents for Reduced Radiation Dose and New Imaging ApplicR01EB015476 · NIBIB · GENERAL ELECTRIC GLOBAL RESEARCH CTR · PI EDIC, PETER, YEH, BENJAMIN M · 2013 to 2016
$3.4M
Preclinical Efficacy of Silicon-based Dual Energy CT Contrast MaterialR41DK104580 · NIDDK · NEXTRAST, INC. · PI BRADLEY, WILLIAM GUERIN · 2014 to 2014
$233k
NIBIB NIH HHS 1R01EB015476NIBIB NIH HHS R01 EB015476NIDDK NIH HHS 1R41DK104580NIDDK NIH HHS R41 DK104580
6 · The paper itself

Abstract

objectiveThe purpose of this study is to describe the appearance and frequency of gas interface artifacts in the jejunum that may mimic severe bowel disease on iodine-density images generated from rapid-voltage-switching dual-energy CT (DECT) scans. MATERIALS AND

methodsTwo readers retrospectively reviewed 108 consecutive abdominal rapid-voltage-switching DECT scans to record the presence of image artifacts in jejunal segments with different degrees of gaseous luminal filling, classified as full, partial, or absent. Readers viewed iodine-density images and corresponding 140-kVp and 65-keV virtual monochromatic images and classified the jejunal artifacts on iodine-density images as pseudostratified appearance of the bowel wall, pseudopneumatosis, pseudohyperenhancement, or pseudohypoenhancement. We correlated the presence of the artifacts with clinical features suggesting bowel disease.

resultsImage artifacts were found in 91 of 108 scans (84.3%), appeared in 148 of 265 jejunal segments (55.8%), and included each type except for pseudohypoenhancement. Artifacts occurred exclusively when gas was present in the bowel lumen and were seen in 59 of 59 (100%) fully gas-distended segments, 89 of 98 (90.8%) partially gas-distended segments, and none of 108 gas-absent segments (p < 0.0001). In fully and partially gas-distended jejunal segments (n = 157), 148 (94.3%) segments had two or more artifacts. None of the patients was found to have clinical bowel-related injury on follow-up of medical records.

conclusionPseudostratified appearance, pseudopneumatosis, and pseudohyperenhancement, but not pseudohypoenhancement, artifacts are common in gas-filled jejunal segments on iodine-density images generated from rapid-voltage-switching DECT scans and are not seen in the corresponding 140-kVp or 65-keV images. Knowledge of the appearance of such iodine-density image artifacts will avoid potential examination interpretation pitfalls.

Indexed as

ArtifactsContrast MediaGasesHumansIodineJejunumPhantoms, ImagingRadiographic Image Interpretation, Computer-AssistedRetrospective StudiesTomography, X-Ray ComputedContrast MediaGasesIodineartifactDECTdual-energy CTjejunumsmall bowel

Identifiers

PMID26797356
PMCPMC4779599

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.