ArticleThe European respiratory journal2016
Traffic-related air pollution and alveolar nitric oxide in southern California children.
Article in The European respiratory journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 56 citations in OpenAlex.
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- Perceptions surrounding the possible interaction between physical activity, pollution and asthma in children and adolescents with and without asthma.BMC public health · 2023Article
- Biomarkers of particulate matter exposure in patients with chronic obstructive pulmonary disease: a systematic review.Journal of thoracic disease · 2023Review
- Personal Exposure to Black Carbon at School and Levels of Fractional Exhaled Nitric Oxide in New York City.Environmental health perspectives · 2021Article
- Hierarchical Bayesian estimation of covariate effects on airway and alveolar nitric oxide.Scientific reports · 2021Article
- The contribution of cooking appliances and residential traffic proximity to aerosol personal exposure.Journal of environmental health science & engineering · 2021Article
- Exposure to traffic-related air pollution and changes in exhaled nitric oxide and DNA methylation in arginase and nitric oxide synthase in children with asthma.Environmental health : a global access science source · 2021Article
- Impact of low-level fine particulate matter and ozone exposure on absences in K-12 students and economic consequences.Environmental research letters : ERL [Web site] · 2020Article
- Ambient air pollution is associated with airway inflammation in older women: a nested cross-sectional analysis.BMJ open respiratory research · 2020Article
- Associations of Timing and Mode of Commuting with In-Transit Black Carbon Exposure and Airway Inflammation: A Pilot Study.Annals of the American Thoracic Society · 2019Article
- Short-term effects of airport-associated ultrafine particle exposure on lung function and inflammation in adults with asthma.Environment international · 2018Article
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
Mechanisms for the adverse respiratory effects of traffic-related air pollution (TRAP) have yet to be established. We evaluated the acute effects of TRAP exposure on proximal and distal airway inflammation by relating indoor nitric oxide (NO), a marker of TRAP exposure in the indoor microenvironment, to airway and alveolar sources of exhaled nitric oxide (FeNO).FeNO was collected online at four flow rates in 1635 schoolchildren (aged 12-15 years) in southern California (USA) breathing NO-free air. Indoor NO was sampled hourly and linearly interpolated to the time of the FeNO test. Estimated parameters quantifying airway wall diffusivity (DawNO) and flux (J'awNO) and alveolar concentration (CANO) sources of FeNO were related to exposure using linear regression to adjust for potential confounders.We found that TRAP exposure indoors was associated with elevated alveolar NO. A 10 ppb higher indoor NO concentration at the time of the FeNO test was associated with 0.10 ppb higher average CANO (95% CI 0.04-0.16) (equivalent to a 7.1% increase from the mean), 4.0% higher J'awNO (95% CI -2.8-11.3) and 0.2% lower DawNO (95% CI -4.8-4.6).These findings are consistent with an airway response to TRAP exposure that was most marked in the distal airways.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.