ArticleLasers in medical science2016
Low-intensity red and infrared lasers affect mRNA expression of DNA nucleotide excision repair in skin and muscle tissue.
Article in Lasers in medical science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 21 citations in OpenAlex.
- Membrane-free bone regeneration using biphasic calcium phosphate, heterologous fibrin biopolymer, and photobiomodulation: anThe journal of venomous animals and toxins including tropical diseases · 2026Article
- Phototoxicity of low doses of light and influence of the spectral composition on human RPE cells.Scientific reports · 2024Article
- Effects of low‑power red laser and blue LED on mRNA levels from DNA repair genes in human breast cancer cells.Lasers in medical science · 2024Article
- The Effects of a 2-W Laser on the Nasolabial Fold of Ageing Individuals Investigated by High-Frequency Ultrasonography: A Nonrandomized Controlled Trial.Journal of lasers in medical sciences · 2022Article
- Photobiomodulation can prevent apoptosis in cells from mouse periodontal ligament.Lasers in medical science · 2020Article
- DNA repair and genomic stability in lungs affected by acute injury.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2019Review
- Photobiomodulation can alter mRNA levels cell death-related.Lasers in medical science · 2019Article
- Low-power laser alters mRNA levels from DNA repair genes in acute lung injury induced by sepsis in Wistar rats.Lasers in medical science · 2019Article
- Photobiomodulation effects on mRNA levels from genomic and chromosome stabilization genes in injured muscle.Lasers in medical science · 2018Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lasers emit light beams with specific characteristics, in which wavelength, frequency, power, fluence, and emission mode properties determine the photophysical, photochemical, and photobiological responses. Low-intensity lasers could induce free radical generation in biological tissues and cause alterations in macromolecules, such as DNA. Thus, the aim of this work was to evaluate excision repair cross-complementing group 1 (ERCC1) and excision repair cross-complementing group 2 (ERCC2) messenger RNA (mRNA) expression in biological tissues exposed to low-intensity lasers. Wistar rat (n = 28, 4 for each group) skin and muscle were exposed to low-intensity red (660 nm) and near-infrared (880 nm) lasers at different fluences (25, 50, and 100 J/cm(2)), and samples of these tissues were withdrawn for RNA extraction, cDNA synthesis, and gene expression evaluation by quantitative polymerase chain reaction. Laser exposure was in continuous wave and power of 100 mW. Data show that ERCC1 and ERCC2 mRNA expressions decrease in skin (p < 0.001) exposed to near-infrared laser, but increase in muscle tissue (p < 0.001). ERCC1 mRNA expression does not alter (p > 0.05), but ERCC2 mRNA expression decreases in skin (p < 0.001) and increases in muscle tissue (p < 0.001) exposed to red laser. Our results show that ERCC1 and ERCC2 mRNA expression is differently altered in skin and muscle tissue exposed to low-intensity lasers depending on wavelengths and fluences used in therapeutic protocols.
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