Evidence map›Paper›PMID 26796362›Full record

ReviewBlood2016

Use of hematopoietic cell transplants to achieve tolerance in patients with solid organ transplants.

Samuel Strober

Abstract readReview
In one paragraph

Review in Blood, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Combined Haploidentical Hematopoetic Stem Cell Transplantation and Liver Transplantation in a Pediatric Patient.International journal of hematology-oncology and stem cell research · 2023
    Article
  6. Article
  7. Helical TomoTherapy Total Lymphoid Irradiation and Hematopoietic Cell Transplantation for Kidney Transplant Tolerance in Rhesus Macaques.Transplant international : official journal of the European Society for Organ Transplantation · 2023
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. Regulatory dendritic cells for human organ transplantation.Transplantation reviews (Orlando, Fla.) · 2019
    Review
  16. Review
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Samuel StroberDepartment of Medicine, Stanford University School of Medicine, Stanford, CA.
Stanford University · US

Funding

TLI/ATG CONDTIONING: KIDNEY/BLOOD STEM CELL TRANSPLANTSP01HL075462 · NHLBI · STANFORD UNIVERSITY · PI ENGLEMAN, EDGAR G. · 2004 to 2020
$27.9M
Role of Dendritic Cells in Mixed Chimerism and ToleranceR01AI118884 · NIAID · STANFORD UNIVERSITY · PI ENGLEMAN, EDGAR G., STROBER, SAMUEL · 2015 to 2019
$1.8M
NHLBI NIH HHS P01 HL075462NHLBI NIH HHS P01-HL075462NIAID NIH HHS R01-AI10376NIAID NIH HHS R01 AI118884NIAID NIH HHS R01-AI118884
6 · The paper itself

Abstract

The goals of tolerance in patients with solid organ transplants are to eliminate the lifelong need for immunosuppressive (IS) drugs and to prevent graft loss due to rejection or drug toxicity. Tolerance with complete withdrawal of IS drugs has been achieved in recipients of HLA-matched and mismatched living donor kidney transplants in 3 medical centers using hematopoietic cell transplants to establish mixed or complete chimerism.

Indexed as

ChimerismImmune ToleranceGraft RejectionGraft SurvivalHaplotypesHematopoietic Stem Cell TransplantationHLA AntigensHumansKidney TransplantationHLA Antigens

Identifiers

PMID26796362
PMCPMC4807420
OpenAlexW2324311462

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.