ArticleDiagnostic pathology2016
IgG4-related inflammatory pseudotumor of the renal pelvis involving renal parenchyma, mimicking malignancy.
Article in Diagnostic pathology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- IgG4-related kidney disease mimicking renal cell carcinoma: a case report and literature review.Frontiers in medicine · 2026Article
- Inflammatory myofibroblastic tumor of the genitourinary tract: a narrative review.Translational andrology and urology · 2024Review
- Renal Manifestations of IgG4-Related Disease: A Concise Review.International journal of nephrology · 2024Review
- A case of IgG4-related interstitial nephritis with ureteral obstruction: case report and literature review.BMC urology · 2023Review
- IgG4-Related Disease Mimicking Unilateral Urothelial Carcinoma: A Rare Case Report and Literature Review.Clinical medicine insights. Case reports · 2023Article
- Immunoglobulin G4-related kidney disease involving the renal pelvis and perirenal fat: A case report.World journal of clinical cases · 2022Article
- Unique case of IgG4-related disease of the renal pelvis involving the inferior vena cava masquerading as locally advanced urothelial cancer.BMJ case reports · 2022Article
- Mimickers of Urothelial Carcinoma and the Approach to Differential Diagnosis.Clinics and practice · 2021Review
- IgG4-related disease mimicking renal pelvis tumor with peritoneal carcinomatosis.Clinical case reports · 2020Article
- Article
- Urinary System Manifestation of IgG4-Related Disease: Clinical, Laboratory, Radiological, and Pathological Spectra of a Chinese Single-Centre Study.Journal of immunology research · 2020Article
- IgG4-related pseudo-tumor of the kidney and multiple organ involvement mimicked malignancy.Urology case reports · 2019Article
- Recent advances in understanding and managing IgG4-related disease.F1000Research · 2017Review
- An overview of the diagnosis and management of immunoglobulin G4-related disease.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2016Review
- Immunoglobulin G4-related renal disease masquerading as renal pelvic tumor.Indian journal of urology : IJU : journal of the Urological Society of IndiaArticle
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Abstract
backgroundIgG4-related disease is a recently recognized systemic disease characterized by storiform fibrosis with infiltration of IgG4-positive plasma cells. In rare incidences, IgG4-related renal disease can present as a solitary mass lesion at renal pelvis and can pose a diagnostic challenge since these lesions mimic malignancy. Herein, we present a rare case of IgG4-related disease presenting as inflammatory pseudotumor lesion, involving the renal pelvis and also neighboring renal parenchyma. CASE PRESENTATION: A 75-year-old man with no history of IgG4-related disease underwent computed tomography (CT) scan for evaluation of prostatic cancer. The CT scan incidentally revealed a mass lesion located at the right renal pelvis. Radiologic findings were highly suggestive of malignancy. Therefore, the patient underwent right nephroureterectomy. Microscopically, the mass lesion showed storiform fibrosis with diffuse and intense inflammatory cell infiltration. Infiltrating cells were mainly histiocytes and plasma cells. Tubulointerstitium adjacent to the lesion also showed fibrosis with abundant plasmacytic infiltration. Immunohistochemical staining revealed the presence of IgG4-positive plasma cells in both the mass lesion and tubulointerstitium (mean of 94/HPF per field).
conclusionConsidering these findings, we diagnosed the mass lesion as IgG4-related inflammatory pseudotumor of the renal pelvis. In patients with renal pelvic masses, IgG4-related inflammatory pesudotumor should be considered in the differential diagnosis to avoid unnecessary surgical intervention.
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