Evidence map›Paper›PMID 26796240›Full record

Trial reportBurns : journal of the International Society for Burn Injuries2016

Effects of whole-body vibration exercise on bone mineral content and density in thermally injured children.

Joel Edionwe, Cameron Hess, Javier Fernandez-Rio, David N Herndon, Clark R Andersen, Gordon L Klein, Oscar E Suman, William E Amonette

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Burns : journal of the International Society for Burn Injuries, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 3 pooled it
2.5field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 3 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Article
  6. Review
  7. Article
  8. The Long-Term Impact of Severe Burn Trauma on Musculoskeletal Health.Journal of burn care & research : official publication of the American Burn Association · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Joel EdionweSchool of Medicine, University of Texas Medical Branch, Galveston, TX, United States.
Cameron HessSchool of Medicine, University of Texas Medical Branch, Galveston, TX, United States.
Javier Fernandez-RioDepartment of Educational Sciences, University of Oviedo, Oviedo, Spain.
David N HerndonDepartment of Surgery, University of Texas Medical Branch , Galveston, TX, United States; Shriners Hospitals for Children(®)-Galveston , Galveston, TX, United States.
Clark R AndersenDepartment of Surgery, University of Texas Medical Branch , Galveston, TX, United States; Shriners Hospitals for Children(®)-Galveston , Galveston, TX, United States.
Gordon L KleinShriners Hospitals for Children(®)-Galveston , Galveston, TX, United States.
Oscar E SumanDepartment of Surgery, University of Texas Medical Branch , Galveston, TX, United States; Shriners Hospitals for Children(®)-Galveston , Galveston, TX, United States. Electronic address: oesuman@utmb.edu.
William E AmonetteDepartment of Clinical Health and Applied Sciences, University of Houston-Clear Lake, Houston, TX, United States.
The University of Texas Medical Branch at Galveston · USShriners Hospitals for Children - Galveston · USUniversidad de Oviedo · ESUniversity of Houston - Clear Lake · US

Funding

MODULATION OF THE POSTBURN HYPERMETABOLIC RESPONSER01GM056687 · NIGMS · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI HERNDON, DAVID N. · 1998 to 2017
$9.0M
Oxandrolone and Exercise: A potent therapy in the rehabilitation from burnsR01HD049471 · NICHD · UNIVERSITY OF TEXAS MED BR GALVESTON · PI SUMAN-VEJAS, OSCAR E. · 2006 to 2019
$5.8M
SIGNALING BY FRIZZLED PROTEINS IN DROSOPHILAR01GM060388 · NIGMS · STANFORD UNIVERSITY · PI NUSSE, ROEL · 2000 to 2003
$381k
NICHD NIH HHS R01 HD049471NIGMS NIH HHS L40 GM072210NIGMS NIH HHS R01 GM056687NIGMS NIH HHS R01 GM060388
6 · The paper itself

Abstract

backgroundLoss of bone mass, muscle mass, and strength leads to significant disability in severely burned children. We assessed the effects of exercise combined with whole-body vibration (WBV) on bone mass, lean mass (LM), and muscle strength in children recovering from burns.

methodsNineteen burned children (≥30% total body surface area [TBSA] burns) were randomly assigned to a 6-week exercise regimen either alone (EX; n=10) or in combination with a 6-week WBV training regimen (EX+WBV; n=9). WBV was performed concurrent to the exercise regimen for 5days/week on a vibrating platform. Dual-energy X-ray absorptiometry quantified bone mineral content (BMC), bone mineral density (BMD), and LM; knee extension strength was assessed using isokinetic dynamometry before and after training. Alpha was set at p<0.05.

resultsBoth groups were similar in age, height, weight, TBSA burned, and length of hospitalization. Whole-body LM increased in the EX group (p=0.041) and trended toward an increase in the EX+WBV group (p=0.055). On the other hand, there were decreases in leg BMC for both groups (EX, p=0.011; EX+WBV, p=0.047), and in leg BMD for only the EX group (EX, p<0.001; EX+WBV, p=0.26). Truncal BMC decreased in only the EX group (EX, p=0.009; EX+WBV, p=0.61), while BMD decreased in both groups (EX, p<0.001; EX+WBV group, p<0.001). Leg strength increased over time in the EX group (p<0.001) and the EX+WBV group (p<0.001; between-group p=0.31).

conclusionsExercise in combination with WBV may help attenuate regional bone loss in children recovering from burns. Studies are needed to determine the optimal magnitude, frequency, and duration of the vibration protocol, with attention to minimizing any potential interference with wound healing and graft closure.

Indexed as

Bone DensityMuscle StrengthAbsorptiometry, PhotonAdolescentBody Surface AreaBone Diseases, MetabolicBurnsChildCombined Modality TherapyExercise TherapyFemaleHumansMalePhysical Therapy ModalitiesVibrationBoneBone contentBone densityExerciseWhole-body vibration

Identifiers

PMID26796240
PMCPMC4880497
OpenAlexW2264840226

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.