ArticleScientific reports2016
A simple and novel way of maintaining constant wall temperature in microdevices.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- The Concept of Making On-Chip Thermal Cycler for RT-PCR Using Conjugate Heat Transfer in Diverging Microchannel.Transactions of the Indian National Academy of Engineering : an international journal of engineering and technology · 2020Article
- Microdevice for plasma separation from whole human blood using bio-physical and geometrical effects.Scientific reports · 2016Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Constant wall temperature /homogeneity in wall temperature is the need of various lab-on-chip devices employed in biological and chemical investigations. However method to maintain this condition does not seem to be available. In this work, a novel and simple way of maintaining constant wall temperature is proposed. A diverging microchannel along with conjugate effects is utilized towards this end. Both measurements and three dimensional numerical simulations are undertaken to prove the design. The investigation has been carried out over a large parameter range (divergence angle: 1-8°; length: 10-30 mm; depth: 86-200 μm; solid-to-fluid thickness ratio: 1.5-4.0, and solid-to-fluid thermal conductivity ratio: 27-646) and input conditions (mass flow rate: 4.17 × 10(-5) -9.17 × 10(-5) kg/s, heat flux: 2.4-9.6 W/cm(2)) which helped in establishing the finding. It is observed that a nearly constant wall temperature condition can be achieved over a large parameter range investigated. A model to arrive at the design parameter values is also proposed. The method is further demonstrated for series of microchannels where we successfully maintain each station at different temperature within ± 1 °C. The finding is therefore significant and can be employed in both single and multi-stage processes such as PCR requiring different constant wall temperature with a fine resolution.
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Registered trials
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