Evidence map›Paper›PMID 26795753›Full record

ArticleScientific reports2016

A simple and novel way of maintaining constant wall temperature in microdevices.

V S Duryodhan, Abhimanyu Singh, Shiv Govind Singh, Amit Agrawal

Abstract read
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. The Concept of Making On-Chip Thermal Cycler for RT-PCR Using Conjugate Heat Transfer in Diverging Microchannel.Transactions of the Indian National Academy of Engineering : an international journal of engineering and technology · 2020
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

V S DuryodhanIndian Institute of Technology Bombay, Powai, Mumbai 400076, India.
Abhimanyu SinghIndian Institute of Technology Bombay, Powai, Mumbai 400076, India.
Shiv Govind SinghIndian Institute of Technology Hyderabad, Hyderabad 502205, India.
Amit AgrawalIndian Institute of Technology Bombay, Powai, Mumbai 400076, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Constant wall temperature /homogeneity in wall temperature is the need of various lab-on-chip devices employed in biological and chemical investigations. However method to maintain this condition does not seem to be available. In this work, a novel and simple way of maintaining constant wall temperature is proposed. A diverging microchannel along with conjugate effects is utilized towards this end. Both measurements and three dimensional numerical simulations are undertaken to prove the design. The investigation has been carried out over a large parameter range (divergence angle: 1-8°; length: 10-30 mm; depth: 86-200 μm; solid-to-fluid thickness ratio: 1.5-4.0, and solid-to-fluid thermal conductivity ratio: 27-646) and input conditions (mass flow rate: 4.17 × 10(-5) -9.17 × 10(-5) kg/s, heat flux: 2.4-9.6 W/cm(2)) which helped in establishing the finding. It is observed that a nearly constant wall temperature condition can be achieved over a large parameter range investigated. A model to arrive at the design parameter values is also proposed. The method is further demonstrated for series of microchannels where we successfully maintain each station at different temperature within ± 1 °C. The finding is therefore significant and can be employed in both single and multi-stage processes such as PCR requiring different constant wall temperature with a fine resolution.

Identifiers

PMID26795753
PMCPMC4726283

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