Evidence map›Paper›PMID 26795673›Full record

Trial reportContemporary clinical trials2016

An exercise trial to reduce cancer related fatigue in African American breast cancer patients undergoing radiation therapy: Design, rationale, and methods.

Chiranjeev Dash, Pamela D Randolph-Jackson, Claudine Isaacs, Mary Mills, Kepher Makambi, Vivian V Watkins, Lucile L Adams-Campbell

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Contemporary clinical trials, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Chiranjeev DashGeorgetown Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, D.C., United States. Electronic address: cd422@georgetown.edu.
Pamela D Randolph-JacksonDepartment of Radiation Oncology, Medstar Washington Hospital Center, Washington, D.C., United States.
Claudine IsaacsGeorgetown Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, D.C., United States.
Mary MillsGeorgetown Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, D.C., United States.
Kepher MakambiGeorgetown Lombardi Comprehensive Cancer Center, Biostatistics & Bioinformatics Shared Resource, Washington, D.C., United States.
Vivian V WatkinsGeorgetown Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, D.C., United States.
Lucile L Adams-CampbellGeorgetown Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, D.C., United States.
Georgetown University Medical Center · USGeorgetown Lombardi Comprehensive Cancer CenterGeorgetown University · USMedStar Washington Hospital Center · US

Funding

Tissue Culture Shared ResourceP30CA051008 · NCI · GEORGETOWN UNIVERSITY · PI Louis M Weiner · 1990 to 2026
$71.5M
Maternal Morbidity and Mortality: Risk Factors, Early Detection and Personalized InterventionUL1TR001409 · NCATS · GEORGETOWN UNIVERSITY · PI GONDRE-LEWIS, MARJORIE C, MELLMAN, THOMAS A · 2015 to 2024
$37.8M
Georgetown-Howard Universities Center for Clinical and Translational Science (GHUUL1TR000101 · NCATS · GEORGETOWN UNIVERSITY · PI MELLMAN, THOMAS A, VERBALIS, JOSEPH G · 2012 to 2015
$19.3M
NCATS NIH HHS UL1 TR000101NCATS NIH HHS UL1TR000101NCATS NIH HHS UL1 TR001409NCI NIH HHS P30 CA051008
6 · The paper itself

Abstract

backgroundCancer related fatigue (CRF) is a common and debilitating side-effect of radiotherapy in breast cancer patients. Physical activity interventions can attenuate CRF but evidence in African-American women with breast cancer is lacking. METHODS/

designThe "Pedlar" Study is a prospective, 8-week structured moderate-intensity exercise intervention, delivered concurrently with radiotherapy, to reduce CRF and improve health-related quality of life among African American breast cancer patients. Forty African American women with breast cancer scheduled to receive radiation therapy at MedStar Washington Hospital Center will be randomized to one of the two trial arms: 1) a facility-based aerobic exercise utilizing a portable stationary pedal exerciser; and 2) a control group. Intervention arm participants will exercise at the hospital either before or after their radiation treatment. Assessments will be conducted at baseline, 4, and 8 weeks. The outcome variables are CRF, biomarkers of inflammation, and health-related quality of life. DISCUSSION: The Pedlar Study will provide preliminary evidence on whether a short-term moderate-intensity exercise intervention might be effective in reducing CRF in African American women undergoing radiotherapy for breast cancer, and whether this effect is mediated by inflammation.

Indexed as

Black or African AmericanAdolescentAdultAgedBreast NeoplasmsClinical ProtocolsExercise TherapyFatigueFemaleHumansMiddle AgedProspective StudiesQuality of LifeRadiation InjuriesResearch DesignYoung AdultAfrican–AmericanBreast cancerClinical trialPhysical activityRadiotherapy

Identifiers

PMID26795673
PMCPMC4818171
OpenAlexW2289317823

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.