ArticlePloS one2016
Association between Maternal Smoking during Pregnancy and Low Birthweight: Effects by Maternal Age.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
26 citing papers in PubMed, 3 syntheses or guidelines pooled it, 60 citations in OpenAlex.
- Association between prenatal environmental tobacco smoke exposure and preterm birth: A systematic review and meta-analysis.Acta obstetricia et gynecologica Scandinavica · 2025Pooled it
- Maternal smoking status during pregnancy and low birth weight in offspring: systematic review and meta-analysis of 55 cohort studies published from 1986 to 2020.World journal of pediatrics : WJP · 2022Pooled it
- Maternal dietary diversity during pregnancy and risk of low birth weight in newborns: a systematic review.Public health nutrition · 2021Pooled it
- Factors Associated With Low Birth Weight in Cambodia: A Secondary Analysis of the Cambodia Demographic and Health Survey, 2021-2022.Journal of pregnancy · 2026Article
- Investigating the Relationship Between Maternal Smoking During Pregnancy and Offspring Handedness: Extending the Proxy Gene-by-Environment Mendelian Randomization Study Design to Include Polygenic Risk Scores.Behavior genetics · 2025Article
- Lifestyle, environment and other major determinants of frailty in older adults: a population-based study from the UK Biobank.Biogerontology · 2025Article
- Linking epidemiology and genomics of maternal smoking during pregnancy in utero and in ageing: a population-based study using human foetuses and the UK Biobank cohort.EBioMedicine · 2025Article
- Perinatal outcomes of women with recurrent pregnancy loss undergoing frozen embryo transfer from the Society of Assisted Reproductive Technology database.Fertility and sterility · 2025Article
- Greenspace Morphology and Preterm Birth: A State-Wide Study in Georgia, United States (2001-2016).Environmental health perspectives · 2024Article
- Household Wealth Gradient in Low Birthweight in India: A Cross-Sectional Analysis.Children (Basel, Switzerland) · 2023Article
- Prenatal tobacco smoke exposure and risk of brain abnormalities on magnetic resonance imaging at term in infants born very preterm.American journal of obstetrics & gynecology MFM · 2023Article
- Impact of Prenatal Nicotine Exposure on Placental Function and Respiratory Neural Network Development.Advances in experimental medicine and biology · 2023Review
- Maternal Metals Exposure and Infant Weight Trajectory: The Japan Environment and Children's Study (JECS).Environmental health perspectives · 2022Article
- Influence of gestational weight gain on baby's birth weight in Addis Ababa, Central Ethiopia: a follow-up study.BMJ open · 2022Article
- Article
- Relationship between Thyroid Status during the First Trimester of Pregnancy and Neonatal Well-Being.Nutrients · 2021Observational
- The Interplay between Maternal Smoking and Genes in Offspring Birth Weight.medRxiv : the preprint server for health sciences · 2020Article
- Smoking cessation in early-pregnancy, gestational weight gain and subsequent risks of pregnancy complications.European journal of obstetrics, gynecology, and reproductive biology · 2020Article
- Epidemiological determinants of low birth weight: A prospective study.Journal of family medicine and primary care · 2020Article
- Examining the Relationship Between Low Birth Weight Occurrence and Passive Measures of Environmental Arsenic by Census Tract in Escambia and Santa Rosa Counties, Florida.Environmental health insights · 2020Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMaternal smoking during pregnancy has been consistently related to low birthweight. However, older mothers, who are already at risk of giving birth to low birthweight infants, might be even more susceptible to the effects of maternal smoking. Therefore, this study aimed to examine the modified association between maternal smoking and low birthweight by maternal age.
methodsData were obtained from a questionnaire survey of all mothers of children born between 2004 and 2010 in Okinawa, Japan who underwent medical check-ups at age 3 months. Variables assessed were maternal smoking during pregnancy, maternal age, gestational age, parity, birth year, and complications during pregnancy. Stratified analyses were performed using a logistic regression model.
resultsIn total, 92641 participants provided complete information on all variables. Over the 7 years studied, the proportion of mothers smoking during pregnancy decreased from 10.6% to 5.0%, while the prevalence of low birthweight did not change remarkably (around 10%). Maternal smoking was significantly associated with low birthweight in all age groups. The strength of the association increased with maternal age, both in crude and adjusted models.
conclusionsConsistent with previous studies conducted in Western countries, this study demonstrates that maternal age has a modifying effect on the association between maternal smoking and birthweight. This finding suggests that specific education and health care programs for older smoking mothers are important to improve their foetal growth.
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