Trial reportThe Journal of pediatrics2016
Predictors of Antimicrobial Resistance among Pathogens Causing Urinary Tract Infection in Children.
Trial report in The Journal of pediatrics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 51 citations in OpenAlex.
- Long-term antibiotics for preventing recurrent urinary tract infection in children.The Cochrane database of systematic reviews · 2019Pooled it
- Interventions for primary vesicoureteric reflux.The Cochrane database of systematic reviews · 2019Pooled it
- Discordance between antibiotic therapy and recurrent urinary tract infections in young children with third-generation cephalosporin-resistant infections.Clinical and experimental pediatrics · 2026Article
- Machine learning model for predicting urinary tract infection risk in febrile children under 3 years of age.Frontiers in pediatrics · 2025Article
- Insights into Hospitalized Children with Urinary Tract Infections: Epidemiology and Antimicrobial Resistance Patterns in Israel-A Single Center Study.Children (Basel, Switzerland) · 2024Article
- Outcomes associated with initial narrow-spectrum versus broad-spectrum antibiotics in children hospitalized with urinary tract infections.Journal of hospital medicine · 2024Article
- Epidemiology of community origin of major multidrug-resistant ESKAPE uropathogens in a paediatric population in South-East Gabon.Antimicrobial resistance and infection control · 2023Article
- Development of a Prediction Model for Antibiotic-Resistant Urinary Tract Infections Using Integrated Electronic Health Records from Multiple Clinics in North-Central Florida.Infectious diseases and therapy · 2022Article
- Rising resistance of urinary tract pathogens in children: a cause for concern.Irish journal of medical science · 2022Article
- The RiVUR Study Outcomes and Implications on the Management of Vesicoureteral Reflux.Archives of nephrology and renal studies · 2022Article
- Examination of Complementary Medicine for Treating Urinary Tract Infections Among Pregnant Women and Children.Frontiers in pharmacology · 2022Review
- Contemporary Management of Urinary Tract Infections in Children.Current treatment options in pediatrics · 2022Review
- Antibiotic Resistance Patterns of Uropathogens Causing Urinary Tract Infections in Children with Congenital Anomalies of Kidney and Urinary Tract.Children (Basel, Switzerland) · 2021Article
- Pyelonephritis in Pediatric Uropathic Patients: Differences from Community-Acquired Ones and Therapeutic Protocol Considerations. A 10-Year Single-Center Retrospective Study.Children (Basel, Switzerland) · 2021Article
- Evaluation of urinalysis and urine culture in children with first-time urinary tract infection.Turkish journal of urology · 2021Article
- Analysis of Community-Acquired Urinary Tract Infection Treatment in Pediatric Patients Requiring Hospitalization: Opportunity for Use of Narrower Spectrum Antibiotics.The Journal of pharmacy technology : jPT : official publication of the Association of Pharmacy Technicians · 2021Article
- Multidrug-resistant organisms in urinary tract infections in children.Pediatric nephrology (Berlin, Germany) · 2020Review
- Risk factors for gentamicin-resistant E. coli in children with community-acquired urinary tract infection.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2019Article
- The association between continuous antibiotic prophylaxis and UTI from birth until initial postnatal imaging evaluation among newborns with antenatal hydronephrosis.Journal of pediatric urology · 2018Article
- Genomic insights into nitrofurantoin resistance mechanisms and epidemiology in clinical Enterobacteriaceae.Future science OA · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 6 institutions in 1 country.
Funding
Abstract
objectiveTo determine which children with urinary tract infection are likely to have pathogens resistant to narrow-spectrum antimicrobials. STUDY
designChildren, 2-71 months of age (n = 769) enrolled in the Randomized Intervention for Children with Vesicoureteral Reflux or Careful Urinary Tract Infection Evaluation studies were included. We used logistic regression models to test the associations between demographic and clinical characteristics and resistance to narrow-spectrum antimicrobials.
resultsOf the included patients, 91% were female and 76% had vesicoureteral reflux. The risk of resistance to narrow-spectrum antibiotics in uncircumcised males was approximately 3 times that of females (OR 3.1; 95% CI 1.4-6.7); in children with bladder bowel dysfunction, the risk was 2 times that of children with normal function (OR 2.2; 95% CI 1.2-4.1). Children who had received 1 course of antibiotics during the past 6 months also had higher odds of harboring resistant organisms (OR 1.6; 95% CI 1.1-2.3). Hispanic children had higher odds of harboring pathogens resistant to some narrow-spectrum antimicrobials.
conclusionsUncircumcised males, Hispanic children, children with bladder bowel dysfunction, and children who received 1 course of antibiotics in the past 6 months were more likely to have a urinary tract infection caused by pathogens resistant to 1 or more narrow-spectrum antimicrobials.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.