ArticleScientific reports2016
A Two-Photon Fluorescent Probe for Lysosomal Thiols in Live Cells and Tissues.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Molecular Probes, Chemosensors, and Nanosensors for Optical Detection of Biorelevant Molecules and Ions in Aqueous Media and Biofluids.Chemical reviews · 2022Review
- Strategic engineering of alkyl spacer length for a pH-tolerant lysosome marker and dual organelle localization.Chemical science · 2021Article
- Fluorescent Probes for Live Cell Thiol Detection.Molecules (Basel, Switzerland) · 2021Review
- Fluorescent probes based on nucleophilic aromatic substitution reactions for reactive sulfur and selenium species: Recent progress, applications, and design strategies.Coordination chemistry reviews · 2021Review
- Detection Sensitivity Enhancement of Naphthalimide PET Fluorescent Probes by 4-Methoxy-Substitution.Molecules (Basel, Switzerland) · 2020Article
- A FRET Based Two-Photon Fluorescent Probe for Visualizing Mitochondrial Thiols of Living Cells and Tissues.Sensors (Basel, Switzerland) · 2020Article
- Thiol-specific fluorogenic agent for live cell non-protein thiol imaging in lysosomes.Analytical and bioanalytical chemistry · 2019Article
- Fluorescent probes for organelle-targeted bioactive species imaging.Chemical science · 2019Review
- Tuning the π-bridge of quadrupolar triarylborane chromophores for one- and two-photon excited fluorescence imaging of lysosomes in live cells.Chemical science · 2019Article
- Lysosome-Targeted Single Fluorescence Probe for Two-Channel Imaging Intracellular SO₂ and Biothiols.Molecules (Basel, Switzerland) · 2019Article
- Unravelling the antitumoral potential of novel bis(thiosemicarbazonato) Zn(II) complexes: structural and cellular studies.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2019Article
- Development of a Highly Selective Two-Photon Probe for Methylglyoxal and its Applications in Living Cells, Tissues, and Zebrafish.Journal of fluorescence · 2019Article
- Selective Screening of Biological Thiols by Means of an Unreported Magenta Interaction and Evaluation Using Smartphones.ACS omega · 2018Article
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Authors and funding
4 authors.
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Abstract
Lysosome-specific fluorescent probes are exclusive to elucidate the functions of lysosomal thiols. Moreover, two-photon microscopy offers advantages of less phototoxicity, better three dimensional spatial localization, deeper penetration depth and lower self-absorption. However, such fluorescent probes for thiols are still rare. In this work, an efficient two-photon fluorophore 1,8-naphthalimide-based probe conjugating a 2,4-dinitrobenzenesulfonyl chloride and morpholine was designed and synthesized, which exhibited high selectivity and sensitivity towards lysosomal thiols by turn-on fluorescence method quantitatively and was successfully applied to the imaging of thiols in live cells and tissues by two-photon microscopy.
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