Observational studyBritish journal of cancer2016
HPV immunisation and increased uptake of cervical screening in Scottish women; observational study of routinely collected national data.
Observational study in British journal of cancer, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Health-related quality of life as measured by the EQ-5D in the prevention, screening and management of cervical disease: A systematic review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2017Pooled it
- A cluster randomized trial of strategies to increase uptake amongst young women invited for their first cervical screen: The STRATEGIC trial.Journal of medical screening · 2018Trial
- Sustained impact of bivalent HPV immunisation on CIN incidence over two rounds of cervical screening.International journal of cancer · 2026Article
- Social factors and age play a significant role in cervical cancer and advanced-stage disease among Danish women.BMC cancer · 2024Article
- Article
- Prevalence of cervical disease at age 20 after immunisation with bivalent HPV vaccine at age 12-13 in Scotland: retrospective population study.BMJ (Clinical research ed.) · 2019Article
- Non-Adherence To Childhood HPV Vaccination Is Associated With Non-Participation In Cervical Cancer ScreeningClinical epidemiology · 2019Article
- Information needs of young women vaccinated against HPV attending colposcopy: a qualitative study.BMC women's health · 2018Article
- Differential misclassification between self-reported status and official HPV vaccination records in Japan: Implications for evaluating vaccine safety and effectiveness.Papillomavirus research (Amsterdam, Netherlands) · 2018Article
- Opportunistic HPV vaccination at age 16-23 and cervical screening attendance in Sweden: a national register-based cohort study.BMJ open · 2018Article
- Impact of HPV vaccination on outcome of cervical cytology screening in Denmark-A register-based cohort study.International journal of cancer · 2018Article
- Effect of HPV vaccination and cervical cancer screening in England by ethnicity: a modelling study.The Lancet. Public health · 2018Article
- Effectiveness of cervical screening after age 60 years according to screening history: Nationwide cohort study in Sweden.PLoS medicine · 2017Article
- Article
- Article
- Impact of partial bivalent HPV vaccination on vaccine-type infection: a population-based analysis.British journal of cancer · 2016Article
- Human Papilloma Virus (HPV) Oral Prevalence in Scotland (HOPSCOTCH): A Feasibility Study in Dental Settings.PloS one · 2016Article
Corrections and comments
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Authors and funding
8 authors at 7 institutions in 2 countries.
Funding
Abstract
backgroundTo measure the uptake of first invitation to cervical screening by vaccine status in a population-based cohort offered HPV immunisation in a national catch-up campaign.
methodsA retrospective observational study of routinely collected data from the Scottish Cervical Screening Programme. Data were extracted and linked from the Scottish Cervical Call Recall System, the Scottish Population Register and the Scottish Index of Multiple Deprivation. Records from 201 023 women born between 1 January 1988 and 30 September 1993 were assessed. Women born in or after 1990 were eligible for the national catch-up programme of HPV immunisation. Attendance for screening was within 12 months of the first invitation at age 20 years.
resultsThere was a significant decline in overall attendance from the 1988 cohort to the 1993 cohort with the adjusted attendance ratio of the 1988 cohort being 1.49 times (95% CI 1.46-1.52) that of the 1993 cohort. Immunisation compensated for this decrease in uptake with unvaccinated individuals having a reduced ratio of attendance compared with those fully vaccinated (RR=0.65, 95% CI 0.64-0.65). Not taking up the opportunity for HPV immunisation was associated with an attendance for screening below the trend line for all women before the availability of HPV immunisation.
conclusionsHPV immunisation is not associated with the reduced attendance for screening that had been feared. Immunised women in the catch-up cohorts appear to be more motivated to attend than unimmunised women, but this may be a result of a greater awareness of health issues. These results, while reassuring, may not be reproduced in routinely immunised women. Continued monitoring of attendance for the first smear and subsequent routine smears is needed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.