ArticleNature communications2016
Broadband single-molecule excitation spectroscopy.
Article in Nature communications, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Fluorescence-Detected Pump-Probe Spectroscopy for Artifact-Free Detection of Stokes Shift Dynamics.The journal of physical chemistry letters · 2025Article
- Interferometric excitation fluorescence lifetime imaging microscopy.Nature communications · 2024Article
- Fluctuations in the Photoluminescence Excitation Spectra of Individual Semiconductor Nanocrystals.The journal of physical chemistry letters · 2024Article
- Fluorescence-Detected Pump-Probe Spectroscopy.Angewandte Chemie (International ed. in English) · 2021Article
- Investigating Single-Molecule Fluorescence Spectral Heterogeneity of Rhodamines Using High-Throughput Single-Molecule Spectroscopy.The journal of physical chemistry letters · 2021Article
- Ultrafast Transient Holographic Microscopy.Nano letters · 2021Article
- Photon-level broadband spectroscopy and interferometry with two frequency combs.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Development of a Multicolor Line-Focus Microscope for Rapid Acquisitions of Excitation Spectra.Biophysical journal · 2020Article
- High-Throughput Single-Molecule Spectroscopy Resolves the Conformational Isomers of BODIPY Chromophores.The journal of physical chemistry letters · 2019Article
- Single-molecule excitation-emission spectroscopy.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Monitoring of Nonadiabatic Effects in Individual Chromophores by Femtosecond Double-Pump Single-Molecule Spectroscopy: A Model Study.Molecules (Basel, Switzerland) · 2019Article
- Excitation-multiplexed multicolor superresolution imaging with fm-STORM and fm-DNA-PAINT.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- Life under the Microscope: Single-Molecule Fluorescence Highlights the RNA World.Chemical reviews · 2018Review
- Rapid and robust control of single quantum dots.Light, science & applications · 2017Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Over the past 25 years, single-molecule spectroscopy has developed into a widely used tool in multiple disciplines of science. The diversity of routinely recorded emission spectra does underpin the strength of the single-molecule approach in resolving the heterogeneity and dynamics, otherwise hidden in the ensemble. In early cryogenic studies single molecules were identified by their distinct excitation spectra, yet measuring excitation spectra at room temperature remains challenging. Here we present a broadband Fourier approach that allows rapid recording of excitation spectra of individual molecules under ambient conditions and that is robust against blinking and bleaching. Applying the method we show that the excitation spectra of individual molecules exhibit an extreme distribution of solvatochromic shifts and distinct spectral shapes. Importantly, we demonstrate that the sensitivity and speed of the broadband technique is comparable to that of emission spectroscopy putting both techniques side-by-side in single-molecule spectroscopy.
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