ArticleEndoscopy international open2016
High efficacy with deep nurse-administered propofol sedation for advanced gastroenterologic endoscopic procedures.
Article in Endoscopy international open, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 29 citations in OpenAlex.
- Young, Healthy, Underweight Women Require Higher Effective Doses of Propofol for Successful Gastroscope Insertion: a Dose-Finding Study Using Dixon's Up-and-Down Method.Drug design, development and therapy · 2025Trial
- The Incidence of Adverse Events in Adults Undergoing Procedural Sedation with Propofol Administered by Non-Anesthetists: A Systematic Review and Meta-Analysis.Diagnostics (Basel, Switzerland) · 2025Review
- Patient satisfaction and safety in the administration of sedation by nursing staff in the digestive endoscopy service: a cross-sectional study.BMC nursing · 2024Article
- Training and Resources Related to the Administration of Sedation by Nurses During Digestive Endoscopy: A Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2024Article
- Efficacy and Safety of Non-Anesthesiologist Administration of Propofol Sedation in Endoscopic Ultrasound: A Propensity Score Analysis.Diagnostics (Basel, Switzerland) · 2020Article
- Paradigm shift: should the elderly undergo propofol sedation for DBE? A prospective cohort study.Frontline gastroenterology · 2018Article
- How to measure quality in endoscopic ultrasound.Annals of translational medicine · 2018Review
- Controversies in ERCP: Indications and preparation.Endoscopic ultrasoundArticle
- Standard reporting elements for the performance of EUS: Recommendations from the FOCUS working group.Endoscopic ultrasoundArticle
- Periprocedural Role of Nurses During Interventional Endoscopic Procedures Under Deep Sedation.Current health sciences journalArticle
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND STUDY
aimsWhereas data on moderate nurse-administered propofol sedation (NAPS) efficacy and safety for standard endoscopy is abundant, few reports on the use of deep sedation by endoscopy nurses during advanced endoscopy, such as Endoscopic Retrograde Cholangiopancreatography (ERCP) and Endoscopic Ultrasound (EUS) are available and potential benefits or hazards remain unclear. The aims of this study were to investigate the efficacy of intermittent deep sedation with propofol for a large cohort of advanced endoscopies and to provide data on the safety. PATIENTS AND
methodsAll available data from patients sedated with intermittent deep NAPS for ERCP, EUS or double balloon enteroscopy (DBE, since the method was implemented in May 2007 through December 2012 were included for evaluation in a retrospective case-control design.
resultsData from 1899 patients undergoing 1899 procedures were included for evaluation. All but one procedure were completed with intermittent deep NAPS. The mean propofol dose was 397 mg (SD: 232.4) and the infusion rate was 23.9 mg/kg. The frequency of hypoxia was 4.3 % and 20 patients needed assisted ventilation (1.1 %). Anesthesiologic support was requested eight times (0.4 %). One patient was intubated due to suspected aspiration.
conclusionsIntermittent deep NAPS for advanced endoscopies in selected patients provided an almost 100 % success rate. However, the rate of hypoxia, hypotension and respiratory support was high compared with previously published data, but the method was still assessed as safe.
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