ArticleMedical journal of the Islamic Republic of Iran2015
Can hand dexterity predict the disability status of patients with multiple sclerosis?
Article in Medical journal of the Islamic Republic of Iran, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 10 citations in OpenAlex.
- Oxidative stress, depressive symptoms, disability, cognitive outcomes and hand dexterity in relapsing-remitting multiple sclerosis patients with mild/moderate disability.IBRO neuroscience reports · 2026Article
- Early Upper Limb Motor Impairment in Multiple Sclerosis Across EDSS Levels: A Case-Control Study.Brain and behavior · 2026Article
- A New Smartphone-Based Cognitive Screening Battery for Multiple Sclerosis (icognition): Validation Study.Journal of medical Internet research · 2025Article
- Design considerations for a multiple sclerosis fatigue mobile app MS Energize: A pragmatic iterative approach using usability testing and resonance checks.Internet interventions · 2021Article
- The Influence of Self-Perception on Manipulative Dexterity in Adults with Multiple Sclerosis.Occupational therapy international · 2021Article
- A Descriptive Cross-Sectional Study of Manipulative Dexterity on Different Subtypes of Multiple Sclerosis.Occupational therapy international · 2020Article
- Do Impairments Predict Hand Dexterity After Distal Radius Fractures? A 6-Month Prospective Cohort Study.Hand (New York, N.Y.) · 2018Article
- Upper Extremity Capability Tests in Multiple Sclerosis.Noro psikiyatri arsivi · 2018Review
- An Exploratory Cross-Sectional Study of the Association Between Regular Cigarette Smoking and Level of Disability, Hand Dexterity, Cognitive Impairment, Fatigue, and Markers of Oxidative Stress in Male Patients With Relapsing-Remitting Multiple Sclerosis.American journal of men's healthArticle
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMultiple Sclerosis (MS) is the most common disabling neurological disease. Hand dysfunction is one of the main complaints of patients with MS. The present study aimed to compare hand dexterity of MS patients with low Expanded Disability Status Scale (EDSS) scores and healthy adults. It also sought to identify the predictors of disability status of patients with MS based on their manual dexterity and demographic characteristics.
methodsIn this cross-sectional study, 60 (16 male/44 female) patients with MS and 60 (19 male/41 female) healthy people, who matched in terms of age and sex, were recruited. Their hand dexterity was evaluated by the Purdue Pegboard Test. The disability status of the MS group was determined by the Expanded Disability Status Scale. The data were analyzed using SPSS15.
resultsThe hand dexterity in MS group even with low EDSS score (1.5 ± 1.07) was weaker than control group. Moreover, the dexterity of dominant hand and alternating two hands coordination subtests of the PPT was a good discriminator between two groups (p<0.001). The results of linear regression analysis suggested dominant hand dexterity and disease duration as predictors of disability status that predict 60.5 per cent of the variation in EDSS scores in patients with MS (p<0.001).
conclusionReduced dominant hand dexterity in patients with MS is a disabling factor. Further research is recommended to determine if early hand rehabilitation can reduce the severity of disability in Patients with MS.
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26793646PMC4715381W2394725827What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.