ArticleJournal of neurophysiology2016
Socially induced serotonergic fluctuations in the male auditory midbrain correlate with female behavior during courtship.
Article in Journal of neurophysiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 32 citations in OpenAlex.
- A Squeak Is Not Enough: Female Presence and Vocal Playback Have Contrasting Effects on c-Fos Expression by Dorsal Raphé Neurons in Lab Mice.Brain sciences · 2026Article
- Hidden in plain sound: the scientific potential of house mouse squeaks.Biology letters · 2025Review
- What matters to a mouse? Effects of internal and external context on male vocal response to female squeaks.PloS one · 2025Article
- Article
- Solitude and serotonin: juvenile isolation alters the covariation between social behavior and cFos expression by serotonergic neurons.Frontiers in neuroscience · 2024Article
- Neuroendocrine mechanisms contributing to the coevolution of sociality and communication.Frontiers in neuroendocrinology · 2023Review
- Listening to your partner: serotonin increases male responsiveness to female vocal signals in mice.Frontiers in human neuroscience · 2023Article
- Non-sensory Influences on Auditory Learning and Plasticity.Journal of the Association for Research in Otolaryngology : JARO · 2022Review
- Cupid's quiver: Integrating sensory cues in rodent mating systems.Frontiers in neural circuits · 2022Review
- Hearing, touching, and multisensory integration during mate choice.Frontiers in neural circuits · 2022Review
- 5-HT1A Receptors Alter Temporal Responses to Broadband Vocalizations in the Mouse Inferior Colliculus Through Response Suppression.Frontiers in neural circuits · 2021Article
- Silence, Solitude, and Serotonin: Neural Mechanisms Linking Hearing Loss and Social Isolation.Brain sciences · 2020Review
- Serotonergic modulation across sensory modalities.Journal of neurophysiology · 2020Review
- Physiological and Behavioral Responses to Vocalization Playback in Mice.Frontiers in behavioral neuroscience · 2020Article
- Sound-induced monoaminergic turnover in the auditory forebrain depends on endocrine state in a seasonally-breeding songbird.Journal of neuroendocrinology · 2018Article
- Putting it in Context: Linking Auditory Processing with Social Behavior Circuits in the Vertebrate Brain.Integrative and comparative biology · 2017Review
- Serotonin modulates response properties of neurons in the dorsal cochlear nucleus of the mouse.Hearing research · 2017Article
- Serotonin, estrus, and social context influence c-Fos immunoreactivity in the inferior colliculus.Behavioral neuroscience · 2016Article
- Involvement of the Serotonin Transporter Gene in Accurate Subcortical Speech Encoding.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Cues from social partners trigger the activation of socially responsive neuromodulatory systems, priming brain regions including sensory systems to process these cues appropriately. The fidelity with which neuromodulators reflect the qualities of ongoing social interactions in sensory regions is unclear. We addressed this issue by using voltammetry to monitor serotonergic fluctuations in an auditory midbrain nucleus, the inferior colliculus (IC), of male mice (Mus musculus) paired with females, and by concurrently measuring behaviors of both social partners. Serotonergic activity strongly increased in male mice as they courted females, relative to serotonergic activity in the same males during trials with no social partners. Across individual males, average changes in serotonergic activity were negatively correlated with behaviors exhibited by female partners, including broadband squeaks, which relate to rejection of males. In contrast, serotonergic activity did not correlate with male behaviors, including ultrasonic vocalizations. These findings suggest that during courtship, the level of serotonergic activity in the IC of males reflects the valence of the social interaction from the perspective of the male (i.e., whether the female rejects the male or not). As a result, our findings are consistent with the hypothesis that neuromodulatory effects on neural responses in the IC may reflect the reception, rather than the production, of vocal signals.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.