ArticleScientific reports2016
The role of motility and chemotaxis in the bacterial colonization of protected surfaces.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed.
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- Collective bacterial condensation is fundamentally constrained by the emergence of active turbulence.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Altering chemotaxis as a strategy to enhance the foraging range of motility-restricted bacteria.Communications biology · 2026Article
- Navigating bacterial motility through chemotaxis: from molecular mechanisms to physiological perspectives.Folia microbiologica · 2025Review
- Collective condensation and auto-aggregation of Escherichia coli in uniform acidic environments.Communications biology · 2024Article
- Anti-Biofilm Effects of Z102-E ofFoods (Basel, Switzerland) · 2024Article
- Production and purification of outer membrane vesicles encapsulating green fluorescent protein fromFrontiers in bioengineering and biotechnology · 2024Article
- CryoEM structure of a post-assembly MS-ring reveals plasticity in stoichiometry and conformation.PloS one · 2023Article
- DegS protease regulates the motility, chemotaxis, and colonization ofFrontiers in microbiology · 2023Article
- Multifunctional Composite Hydrogels for Bacterial Capture, Growth/Elimination, and Sensing Applications.ACS applied materials & interfaces · 2022Review
- Dynamic alterations in the lung microbiota in a rat model of lipopolysaccharide-induced acute lung injury.Scientific reports · 2022Article
- Bacterial Proprioception: Can a Bacterium Sense Its Movement?Frontiers in microbiology · 2022Review
- Multiple functions of flagellar motility and chemotaxis in bacterial physiology.FEMS microbiology reviews · 2021Review
- Putative RNA Ligase RtcB Affects the Switch between T6SS and T3SS inInternational journal of molecular sciences · 2021Article
- Dependency of active pressure and equation of state on stiffness of wall.Scientific reports · 2021Article
- A distinct growth physiology enhances bacterial growth under rapid nutrient fluctuations.Nature communications · 2021Article
- The ecological roles of microbial lipopeptides: Where are we going?Computational and structural biotechnology journal · 2021Review
- Bacterial surface motility is modulated by colony-scale flow and granular jamming.Journal of the Royal Society, Interface · 2020Article
- A Novel Lysophosphatidic Acid Acyltransferase ofBiomolecules · 2020Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Internal epithelial surfaces in humans are both oxygenated and physically protected by a few hundred microns thick hydrogel mucosal layer, conditions that might support bacterial aerotaxis. However, the potential role of aerotaxis in crossing such a thin hydrogel layer is not clear. Here, we used a new setup to study the potential role of motility and chemotaxis in the bacterial colonization of surfaces covered by a thin hydrogel layer and subjected to a vertical oxygen gradient. Using the bacterium Escherichia coli, we show that both non-motile and motile-but-non-chemotactic bacteria could barely reach the surface. However, an acquired mutation in the non-chemotactic bacteria that altered their inherent swimming behavior led to a critical enhancement of surface colonization. Most chemotactic strains accumulated within the bulk of the hydrogel layer, except for the MG1655 strain, which showed a unique tendency to accumulate directly at the oxygenated surface and thus exhibited distinctly enhanced colonization. Even after a long period of bacterial growth, non-motile bacteria could not colonize the hydrogel. Thus, switching motility, which can be spontaneously acquired or altered in vivo, is critical for the colonization of such protected surfaces, whereas aerotaxis capacity clearly expedites surface colonization, and can lead to diverse colonization patterns.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.