Evidence map›Paper›PMID 26792221›Full record

Trial reportBMJ open2016

Lay health supporters aided by a mobile phone messaging system to improve care of villagers with schizophrenia in Liuyang, China: protocol for a randomised control trial.

Dong Roman Xu, Wenjie Gong, Eric D Caine, Shuiyuan Xiao, James P Hughes, Marie Ng, Jane Simoni, Hua He, Kirk L Smith, Henry Shelton Brown and 1 more

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMJ open, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Trial
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Dong Roman XuSun Yat-sen Global Health Institute (SGHI), School of Public Health, Sun Yat-sen University, Guangzhou, Guangdong, China Department of Global Health, University of Washington, Seattle, Washington, USA.ORCID http://orcid.org/0000-0001-7438-632X
Wenjie GongXiangya School of Public Health, Central South University, Changsha, Hunan, China Department of Psychiatry, University of Rochester Medical Center, Rochester, New York, USA.
Eric D CaineDepartment of Psychiatry, University of Rochester Medical Center, Rochester, New York, USA.
Shuiyuan XiaoXiangya School of Public Health, Central South University, Changsha, Hunan, China.
James P HughesDepartment of Biostatistics, University of Washington, Seattle, Washington, USA.
Marie NgInstitute for Health Metrics and Evaluation, University of Washington, Seattle, Washington, USA.
Jane SimoniDepartment of Phycology, University of Washington, Seattle, Washington, USA.
Hua HeDepartment of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, Louisiana, USA.
Kirk L SmithDivision of Health Promotion and Behavioral Sciences, University of Texas Health Science Center School of Public Health at Houston, Houston, Texas, USA.
Henry Shelton BrownAustin Regional Campus Michael & Susan Dell Center for Healthy Living, UTHealth School of Public Health, Austin, Texas, USA.
Stephen GloydDepartment of Global Health, University of Washington, Seattle, Washington, USA.

Funding

Northern/Pacific Universities Global Health Research Training ConsortiumR25TW009345 · FIC · UNIVERSITY OF WASHINGTON · PI KOLARS, JOSEPH C., NERURKAR, VIVEK RAMCHANDRA · 2012 to 2016
$5.9M
China-Rochester Suicide Research Training Program (CRSRT)D43TW009101 · FIC · UNIVERSITY OF ROCHESTER · PI CAINE, ERIC D. · 2011 to 2015
$1.2M
FIC NIH HHS D43 TW009101FIC NIH HHS D43TW009101FIC NIH HHS R25 TW009345FIC NIH HHS R25TW009345
6 · The paper itself

Abstract

introductionSchizophrenia is a severe, chronic and disabling mental illness. Non-adherence to medication and relapse may lead to poorer patient function. This randomised controlled study, under the acronym LEAN (Lay health supporter, e-platform, award, and iNtegration), is designed to improve medication adherence and high relapse among people with schizophrenia in resource poor settings. METHODS/ANALYSIS: The community-based LEAN has four parts: (1) Lay health supporters (LHSs), mostly family members who will help supervise patient medication, monitor relapse and side effects, and facilitate access to care, (2) an E-platform to support two-way mobile text and voice messaging to remind patients to take medication; and alert LHSs when patients are non-adherent, (3) an Award system to motivate patients and strengthen LHS support, and (4) iNtegration of the efforts of patients and LHSs with those of village doctors, township mental health administrators and psychiatrists via the e-platform. A random sample of 258 villagers with schizophrenia will be drawn from the schizophrenic '686' Program registry for the 9 Xiang dialect towns of the Liuyang municipality in China. The sample will be further randomised into a control group and a treatment group of equal sizes, and each group will be followed for 6 months after launch of the intervention. The primary outcome will be medication adherence as measured by pill counts and supplemented by pharmacy records. Other outcomes include symptoms and level of function. Outcomes will be assessed primarily when patients present for medication refill visits scheduled every 2 months over the 6-month follow-up period. Data from the study will be analysed using analysis of covariance for the programme effect and an intent-to-treat approach. ETHICS AND DISSEMINATION: University of Washington: 49464 G; Central South University: CTXY-150002-6. Results will be published in peer-reviewed journals with deidentified data made available on FigShare. TRIAL REGISTRATION NUMBER: ChiCTR-ICR-15006053; Pre-results.

Indexed as

CaregiversCell PhoneText MessagingAntipsychotic AgentsChinaClinical ProtocolsHumansMedically Underserved AreaMedication AdherenceQuality ImprovementRural Health ServicesSchizophreniaTelemedicineAntipsychotic Agents“686” programimplementation sciencelay health workermedication adherencemHealthschizophrenia

Identifiers

PMID26792221
PMCPMC4735204

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.