ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2017
White matter hyperintensity microstructure in amyloid dysmetabolism.
Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- White matter hyperintensities and the risk of vascular dementia: a systematic review and meta-analysis.PeerJ · 2025Pooled it
- Volume and Permeability of White Matter Hyperintensity on Cognition: A DCE Imaging Study of an Older Cohort With and Without Cognitive Impairment.Journal of magnetic resonance imaging : JMRI · 2025Article
- Deep medullary veins disruption in cerebral small vessel disease: links to AI-quantified lesions and cognitive decline.Frontiers in neurology · 2025Article
- Exercise-mediated cerebrovascular repair in Alzheimer's disease: from pathophysiology to therapeutic precision.Frontiers in aging neuroscience · 2025Review
- Emerging Links between Cerebral Blood Flow Regulation and Cognitive Decline: A Role for Brain Microvascular Pericytes.Aging and disease · 2023Review
- Associations of β-Amyloid and Vascular Burden With Rates of Neurodegeneration in Cognitively Normal Members of the 1946 British Birth Cohort.Neurology · 2022Article
- Deep medullary veins are associated with widespread brain structural abnormalities.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022Article
- Amyloid PET imaging and dementias: potential applications in detecting and quantifying early white matter damage.Alzheimer's research & therapy · 2022Article
- Comparison of Diffusion Tensor Imaging Metrics in Normal-Appearing White Matter to Cerebrovascular Lesions and Correlation with Cerebrovascular Disease Risk Factors and Severity.International journal of biomedical imaging · 2022Article
- Role of White Matter Hyperintensities and Related Risk Factors in Vascular Cognitive Impairment: A Review.Biomolecules · 2021Review
- Brain amyloid and vascular risk are related to distinct white matter hyperintensity patterns.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021Article
- Decreased visible deep medullary veins is a novel imaging marker for cerebral small vessel disease.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2020Article
- The effect of white matter signal abnormalities on default mode network connectivity in mild cognitive impairment.Human brain mapping · 2020Article
- Metabolic Syndrome and Amyloid Accumulation in the Aging Brain.Journal of Alzheimer's disease : JAD · 2018Article
- [18F]-Flutemetamol Uptake in Cortex and White Matter: Comparison with Cerebrospinal Fluid Biomarkers and [18F]-Fludeoxyglucose.Journal of Alzheimer's disease : JAD · 2018Article
- Influence of cerebrovascular disease on brain networks in prodromal and clinical Alzheimer's disease.Brain : a journal of neurology · 2017Article
- Advanced Neuroimaging of Cerebral Small Vessel Disease.Current treatment options in cardiovascular medicine · 2017Review
- Cerebrospinal Fluid Levels of Amyloid Beta 1-43 Mirror 1-42 in Relation to Imaging Biomarkers of Alzheimer's Disease.Frontiers in aging neuroscience · 2017Article
- Amyloid Dysmetabolism Relates to Reduced Glucose Uptake in White Matter Hyperintensities.Frontiers in neurology · 2016Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Accumulating evidence suggests associations between cerebrovascular disease (CVD) and Alzheimer's disease (AD). White matter hyperintensities of presumed vascular origin (WMHs) are increased in subjects with mild cognitive impairment (MCI) and AD, but the exact pathomechanistic link is unknown. The current study investigated effects of amyloid dysmetabolism on the microstructure of WMHs in subjects with MCI or subjective cognitive decline (N = 51), dichotomized according to pathological or normal levels of amyloid-β peptide (Aβ
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.