ArticleParasites & vectors2016
The genetic diversity and geographical separation study of Oncomelania hupensis populations in mainland China using microsatellite loci.
Article in Parasites & vectors, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Development of a SYBR Green-Based Real-Time PCR Assay to DetectTropical medicine and infectious disease · 2025Article
- Genetic diversity and structure of Oncomelania hupensis snails in an area where Schistosoma japonicum transmission has been interrupted for nearly 30 years.Parasite (Paris, France) · 2025Article
- Genetic differentiation of Oncomelania hupensis robertsoni in hilly regions of China: Using the complete mitochondrial genome.PLoS neglected tropical diseases · 2024Article
- The genetic diversity of Oncomelania hupensis robertsoni, intermediate hosts of Schistosoma japonicum in hilly regions of China, using microsatellite markers.Parasites & vectors · 2024Article
- Population Genetics ofTropical medicine and infectious disease · 2023Article
- Integrating genomic and epidemiologic data to accelerate progress toward schistosomiasis elimination.eLife · 2022Review
- Genetic diversity and structure of Oncomelania hupensis hupensis in two eco-epidemiological settings as revealed by the mitochondrial COX1 gene sequences.Molecular biology reports · 2022Article
- Schistosomiasis then and now: what has changed in the last 100 years?Parasitology · 2020Review
- Population Structure and Dynamics of Helminthic Infection: Schistosomiasis.Microbiology spectrum · 2019Review
- Asian Schistosomiasis: Current Status and Prospects for Control Leading to Elimination.Tropical medicine and infectious disease · 2019Review
- Schistosoma japonicum transmission risk maps at present and under climate change in mainland China.PLoS neglected tropical diseases · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOncomelania hupensis is the unique intermediate host of Schistosoma japonicum, which plays a crucial role in the transmission of schistosomiasis. The endemic area of S. japonicum is strictly consistent with the geographical distribution of O. hupensis.
methodsA total of 24 populations of O. hupensis from four ecological landscapes were selected for analysis of genetic diversity by screening eight microsatellite DNA polymorphic loci.
resultsThe number of alleles per locus ranged from 29 to 70 with an average of 45.625 and that of effective alleles were 18.5 to 45.8 with an average of 27.4. The observed (Ho) and expected (He) heterozygosities varied from 0.331 to 0.57 and from 0.888 to 0.974, respectively. The mean of polymorphism information content (PIC) for all populations was 0.940, appearing polymorphic for all loci. For the fixation index of F-Statistics, Fit and Fst were 54.95 and 37.62%, respectively. Variation of O. hupensis chiefly exists among individuals, accounting for 60.58% of the total variation determined by Analysis of Molecular Variation (AMOVA). Variation among individuals within populations, among populations within groups and among groups only accounted for 26.60, 8.04 and 4.78%, respectively. This distribution of variation suggests that genetic differences principally originate from within-populations rather than among-populations. Moreover, UPGMA cluster analysis showed that the populations spreading within middle and lower reaches of the Yangtze River (HBWH, JSYZ, JXNC, HNHS, JXJJ, AHWW, HBJL, JXDC, HNNX, JSYZJZ, ZJJH, AHNG and AHWJ) clustered together first, then gathered with the populations in the high mountains (SCMS, SCYA, SCPJ, YNEY, SCLS, YNWS and SCXC), coastal hills (FJFQ and FJFZ) and Karst landform (GXBS and GXYZ) successively.
conclusionThis study provides novel insight into the theoretical source of genetic differentiation of Oncomelania hupensis in mainland China, which is critical for the epidemiological investigation and surveillance of S. japonicum.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.