ArticleHypertension research : official journal of the Japanese Society of Hypertension2016
Abdominal obesity and hypertension: a double burden to the heart.
Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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30 citing papers in PubMed, 38 citations in OpenAlex.
- Heart Rate Variability in Patients with Hypertension: the Effect of Metabolic Syndrome and Antihypertensive Treatment.Cardiovascular therapeutics · 2020Trial
- The impact of diet and sociodemographic factors on cardiovascular health among students at Chimborazo polytechnic high school and State University of Milagro.Frontiers in public health · 2025Article
- Obesity-Related Hemodynamic Alterations in Patients with Cushing's Disease.Journal of clinical medicine · 2024Article
- Genetically predicted plasma cortisol and common chronic diseases: A Mendelian randomization study.Clinical endocrinology · 2024Article
- The characteristics of elevated blood pressure in abdominal obesity correspond to primary hypertension: a cross-sectional study.BMC cardiovascular disorders · 2023Article
- Very low-calorie ketogenic diet (VLCKD): an antihypertensive nutritional approach.Journal of translational medicine · 2023Article
- Association between Arterial Hypertension and Laboratory Markers, Body Composition, Obstructive Sleep Apnea and Autonomic Parameters in Obese Patients.Arquivos brasileiros de cardiologia · 2023Article
- Prevalence and Predictors of Combined Body Mass Index and Waist Circumference Among Indian Adults.International journal of public health · 2023Article
- Physiological Changes and Pathological Pain Associated with Sedentary Lifestyle-Induced Body Systems Fat Accumulation and Their Modulation by Physical Exercise.International journal of environmental research and public health · 2021Review
- Longitudinal Change in Myocardial Function and Clinical Parameters in Middle-Aged Subjects: A 3-Year Follow-up Study.Diabetes & metabolism journal · 2021Article
- Abdominal Obesity, Adipokines and Non-communicable Diseases.The Journal of steroid biochemistry and molecular biology · 2020Review
- Clustering of Elevated Blood Pressure, Elevated Blood Glucose, and Abdominal Obesity Among Adults in Dire Dawa: A Community-Based Cross-Sectional Study.Diabetes, metabolic syndrome and obesity : targets and therapy · 2020Article
- Association between epicardial adipose tissue thickness and parameters of target organ damage in patients undergoing coronary angiography.Hypertension research : official journal of the Japanese Society of Hypertension · 2019Article
- Is leptin protective against heart failure with preserved ejection fraction? A complex interrelationship among leptin, obesity, and left ventricular hypertrophy.Hypertension research : official journal of the Japanese Society of Hypertension · 2019Article
- Percentage of free fat mass is associated with elevated blood pressure in healthy Chinese children.Hypertension research : official journal of the Japanese Society of Hypertension · 2019Article
- Identification of Optimal Baseline Blood Pressure Predicting Postoperative Digestive Tract Cancer-Specific Mortality in the FIESTA Cohort Involving 6865 Patients.Journal of Cancer · 2019Article
- Association between abdominal obesity and increased risk for the development of hypertension regardless of physical activity: A nationwide population-based study.Journal of clinical hypertension (Greenwich, Conn.) · 2018Article
- An interesting cross-talk between the glucagon-like peptide-1 receptor axis and angiotensin receptor pathway for modulation of renal sodium handling in obesity.Hypertension research : official journal of the Japanese Society of Hypertension · 2018Article
- Higher plasma leptin levels are associated with reduced left ventricular mass and left ventricular diastolic stiffness in black women: insights from the Genetic Epidemiology Network of Arteriopathy (GENOA) study.Hypertension research : official journal of the Japanese Society of Hypertension · 2018Article
- Wrist circumference is associated with increased systolic blood pressure in children with overweight/obesity.Hypertension research : official journal of the Japanese Society of Hypertension · 2018Article
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6 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Abdominal obesity (AO) is strongly associated with increased cardiovascular risk in hypertensives. Visceral adipose tissue has an important part in water retention, the sympathetic nervous system and renin-angiotensin-aldosterone system activation, which may influence central and systemic hemodynamics. The aim of this study was to estimate the relationship between AO and the hemodynamic profile of patients with arterial hypertension (AH). The clinical evaluation of 144 hypertensives included the following: (1) echocardiographic assessment of the left ventricular ejection fraction (LVEF), the global longitudinal systolic strain (GLSS) and diastolic function (E/A-phase ratio of mitral flow early (E) and late (A) and E/e'-ratio of early mitral flow and mitral septal annulus early diastolic velocity (e')); (2) the applanation tonometry including the central pulse pressure (CPP) and augmentation index (AI); and (3) the impedance cardiography, acceleration index (ACI), velocity index (VI), systemic vascular resistance index (SVRI) and total artery compliance (TAC). Obese hypertensives in comparison with non-obese ones were characterized with the following values: (1) lower echocardiographic (GLSS: -17.2±2.5% vs. -19.0±2.8%, P=0.0002) and impedance indices of left ventricular performance (VI: 44.8±12.4 vs. 51.6±14.2 × 1000*Ω* s(-1), P=0.006; ACI: 66.7±27.8 vs. 79.1±31.2 100*Ω* s(-)(2), P=0.003) and (2) worse diastolic function (e': 9.08±2.69 vs. 10.39±2.34 cm*s(-1), P=0.003; E/e': 7.54±1.81 vs. 6.74±1.40, P=0.007; E/A: 1.02±0.34 vs. 1.15±0.33, P=0.008). No relevant differences for gender, age, blood pressure, heart rate, LVEF, SVRI, TAC, CPP and AI were identified. AH and AO have overlapping effects on cardiovascular hemodynamics. At the early asymptomatic stage, this overlap is exhibited in the impaired cardiac function.
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