Evidence map›Paper›PMID 26790996›Full record

ArticleJournal of the Royal Society, Interface2016

Self-enforcing regional vaccination agreements.

Petra Klepac, Itamar Megiddo, Bryan T Grenfell, Ramanan Laxminarayan

Abstract read
In one paragraph

Article in Journal of the Royal Society, Interface, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Petra KlepacDepartment of Applied Mathematics and Theoretical Physics, University of Cambridge, Cambridge, UK pklepac@alum.mit.edu.
Itamar MegiddoCenter for Disease Dynamics, Economics and Policy, Washington, DC 20036, USA.ORCID http://orcid.org/0000-0001-8391-6660
Bryan T GrenfellEcology and Evolutionary Biology, Princeton University, Princeton, NJ 08544, USA Woodrow Wilson School of Public and International Affairs, Princeton University, Princeton, NJ 08544, USA Fogarty International Center, National Institutes of Health, Bethesda, MD 20892, USA.
Ramanan LaxminarayanCenter for Disease Dynamics, Economics and Policy, Washington, DC 20036, USA Ecology and Evolutionary Biology, Princeton University, Princeton, NJ 08544, USA Public Health Foundation of India, New Delhi 110070, India.

Funding

Scientific and Technical Computing CoreP2CHD047879 · NICHD · PRINCETON UNIVERSITY · PI SALGANIK, MATTHEW J. · 2014 to 2018
$2.0M
NICHD NIH HHS P2C HD047879
6 · The paper itself

Abstract

In a highly interconnected world, immunizing infections are a transboundary problem, and their control and elimination require international cooperation and coordination. In the absence of a global or regional body that can impose a universal vaccination strategy, each individual country sets its own strategy. Mobility of populations across borders can promote free-riding, because a country can benefit from the vaccination efforts of its neighbours, which can result in vaccination coverage lower than the global optimum. Here we explore whether voluntary coalitions that reward countries that join by cooperatively increasing vaccination coverage can solve this problem. We use dynamic epidemiological models embedded in a game-theoretic framework in order to identify conditions in which coalitions are self-enforcing and therefore stable, and thus successful at promoting a cooperative vaccination strategy. We find that countries can achieve significantly greater vaccination coverage at a lower cost by forming coalitions than when acting independently, provided a coalition has the tools to deter free-riding. Furthermore, when economically or epidemiologically asymmetric countries form coalitions, realized coverage is regionally more consistent than in the absence of coalitions.

Indexed as

Models, ImmunologicalVaccinationAnimalsHumansepidemic dynamicsmetapopulationregional cooperationSIR modeltransboundary movement

Identifiers

PMID26790996
PMCPMC4759795

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.