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ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2016

AmbuFlex: tele-patient-reported outcomes (telePRO) as the basis for follow-up in chronic and malignant diseases.

Liv Marit Valen Schougaard, Louise Pape Larsen, Anne Jessen, Per Sidenius, Liv Dorflinger, Annette de Thurah, Niels Henrik Hjollund

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Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers, 5 of them syntheses that pooled it.

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85citing papers in PubMed, 5 pooled it
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

85 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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  4. Remote symptom monitoring integrated into electronic health records: A systematic review.Journal of the American Medical Informatics Association : JAMIA · 2020
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  8. Patient-Reported Outcome Measures in the Emergency Department: A Scoping Review.Journal of the American College of Emergency Physicians open · 2026
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  10. From framework to practice: applying the proteus-practice framework to learn lessons for integrating PROs in clinical care.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
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  13. Do non-responders of a geriatric screening questionnaire face lower one-year survival compared to responders? A retrospective cohort study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
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25 more citing papers are in PubMed but not listed here.

4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Liv Marit Valen SchougaardAmbuFlex/WestChronic, Regional Hospital West Jutland, Herning, Denmark. livschou@rm.dk.
Louise Pape LarsenAmbuFlex/WestChronic, Regional Hospital West Jutland, Herning, Denmark.
Anne JessenAmbuFlex/WestChronic, Regional Hospital West Jutland, Herning, Denmark.
Per SideniusDepartment of Neurology, Aarhus University Hospital, Aarhus, Denmark.
Liv DorflingerThe Danish Cancer Society, Copenhagen, Denmark.
Annette de ThurahDepartment of Rheumatology, Aarhus University Hospital, Aarhus, Denmark.
Niels Henrik HjollundAmbuFlex/WestChronic, Regional Hospital West Jutland, Herning, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeA tele-patient-reported outcome (telePRO) model includes outpatients' reports of symptoms and health status from home before or instead of visiting the outpatient clinic. In the generic PRO system, AmbuFlex, telePRO is used to decide whether a patient needs an outpatient visit and is thus a tool for better symptom assessment, more patient-centred care, and more efficient use of resources. Specific PROs are developed for each patient group. In this paper we describe our experiences with large-scale implementations of telePRO as the basis for follow-up in chronic and malignant diseases using the generic PRO system AmbuFlex.

methodsThe AmbuFlex concept consists of three generic elements: PRO data collection, PRO-based automated decision algorithm, and PRO-based graphical overview for clinical decision support. Experiences were described with respect to these elements.

resultsBy December 2015, AmbuFlex was implemented in nine diagnostic groups in Denmark. A total of 13,135 outpatients from 15 clinics have been individually referred. From epilepsy clinics, about 70 % of all their outpatients were referred. The response rates for the initial questionnaire were 81-98 %. Of 8256 telePRO-based contacts from epilepsy outpatients, up to 48 % were handled without other contact than the PRO assessment. Clinicians as well as patients reported high satisfaction with the system.

conclusionThe results indicate that telePRO is feasible and may be recommended as the platform for follow-up in several patient groups with chronic and malignant diseases and with many consecutive outpatient contacts.

Indexed as

Chronic DiseaseHealth Status IndicatorsNeoplasmsPatient Outcome AssessmentQuality of LifeAmbulatory CareDenmarkFollow-Up StudiesHumansSurveys and QuestionnairesSymptom AssessmentTelemedicineClinical practiceePROOutpatient clinicOutpatient follow-upPatient-reported outcomestelePRO

Identifiers

PMID26790427
PMCPMC4759231

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.