Evidence map›Paper›PMID 26790340›Full record

ArticleThe Journal of the Association of Nurses in AIDS Care : JANAC

Identifying Symptom Patterns in People Living With HIV Disease.

Natalie L Wilson, Andres Azuero, David E Vance, Joshua S Richman, Linda D Moneyham, James L Raper, Sonya L Heath, Mirjam-Colette Kempf

Abstract read
In one paragraph

Article in The Journal of the Association of Nurses in AIDS Care : JANAC. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  4. Observational
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  19. Past and future of HIV infection. A document based on expert opinion.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Natalie L Wilson
Andres Azuero
David E Vance
Joshua S Richman
Linda D Moneyham
James L Raper
Sonya L Heath
Mirjam-Colette Kempf

Funding

Virology CoreP30AI027767 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI OLAF KUTSCH · 1988 to 2026
$84.1M
The Brown Initiative in HIV and AIDS Clinical Research for Minority CommunitiesR25MH083620 · NIMH · MIRIAM HOSPITAL · PI NUNN, AMY STEWART · 2008 to 2025
$3.7M
Gastrointestinal Symptoms and Microbial Translocation in HIV+ VeteransIK3HX001430 · VA · BIRMINGHAM VA MEDICAL CENTER · PI WILSON, NATALIE LYNN · 2015 to 2015
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HSRD VA IK3 HX001430NIAID NIH HHS P30 AI027767NIMH NIH HHS R25 MH083620NIMH NIH HHS R25MH083620
6 · The paper itself

Abstract

Symptoms guide disease management, and patients frequently report HIV-related symptoms, but HIV symptom patterns reported by patients have not been described in the era of improved antiretroviral treatment. The objectives of our study were to investigate the prevalence and burden of symptoms in people living with HIV and attending an outpatient clinic. The prevalence, burden, and bothersomeness of symptoms reported by patients in routine clinic visits during 2011 were assessed using the 20-item HIV Symptom Index. Principal component analysis was used to identify symptom clusters and relationships between groups using appropriate statistic techniques. Two main clusters were identified. The most prevalent and bothersome symptoms were muscle aches/joint pain, fatigue, and poor sleep. A third of patients had seven or more symptoms, including the most burdensome symptoms. Even with improved antiretroviral drug side-effect profiles, symptom prevalence and burden, independent of HIV viral load and CD4+ T cell count, are high.

Indexed as

Cost of IllnessAdultAgedAlabamaAmbulatory Care FacilitiesAntiretroviral Therapy, Highly ActiveAnxietyCD4 Lymphocyte CountFatigueFemaleHIV InfectionsHumansMaleMiddle AgedPainPrevalencefatigueHIVpainsymptom burdensymptom prevalencesymptoms

Identifiers

PMID26790340
PMCPMC4916902

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.