Evidence map›Paper›PMID 26789991›Full record

ArticleJournal of preventive medicine and hygiene2015

Budget impact analysis of universal rotavirus vaccination in the Local Health Unit 11 Empoli, Tuscany, Italy.

S Guarducci, C Lorini, M Balli, M Donzellini, P Filidei, E Mugnaini, A Silva, G Mazzoni, G Bonaccorsi, P Bonanni and 1 more

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In one paragraph

Article in Journal of preventive medicine and hygiene, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it

0cells of the map it votes in

2citing papers in PubMed, 1 pooled it

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

Accounting for Adverse Events Following Immunization in Economic Evaluation: Systematic Review of Economic Evaluations of Pediatric Vaccines Against Pneumococcus, Rotavirus, Human Papillomavirus, Meningococcus and Measles-Mumps-Rubella-Varicella.PharmacoEconomics · 2023
Pooled it
Parents' insights after pediatric hospitalization due to rotavirus gastroenteritis in Italy.Human vaccines & immunotherapeutics · 2017
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

S GuarducciSpecialization in Hygiene and Preventive Medicine, University of Florence, Italy;

C LoriniDepartment of Health Sciences, University of Florence, Italy;

M BalliSpecialization in Hygiene and Preventive Medicine, University of Florence, Italy;

M DonzelliniSpecialization in Hygiene and Preventive Medicine, University of Florence, Italy;

P FilideiDepartment of Prevention, Unit of Hygiene and Public Health/Sport Medicine, Local Health Unit 11, Empoli, Italy;

E MugnainiDepartment of Prevention, Unit of Hygiene and Public Health/Sport Medicine, Local Health Unit 11, Empoli, Italy;

A SilvaDepartment of Prevention, Unit of Hygiene and Public Health/Sport Medicine, Local Health Unit 11, Empoli, Italy;

G MazzoniDepartment of Prevention, Unit of Hygiene and Public Health/Sport Medicine, Local Health Unit 11, Empoli, Italy;

G BonaccorsiDepartment of Clinical and Experimental Medicine, University of Florence.

P BonanniDepartment of Health Sciences, University of Florence, Italy;

S BoccaliniDepartment of Health Sciences, University of Florence, Italy;

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRotavirus (RV) infection is the first cause of acute viral gastroenteritis in children under five years of age all over the world; it mainly affects children between six and 24 months of age and can cause serious acute diarrhoea and dehydration. The aim of this study is to perform the budget impact analysis of universal rotavirus vaccination in the Local Health Unit (LHU) 11 Empoli, Tuscany, Italy.

methodsAn ad hoc mathematical simulation model was developed to evaluate the budget impact analysis of 5-years universal rotavirus vaccination. Particularly, incidence of rotavirus gastroenteritis (RVGE), hospitalizations, nosocomial diarrhoea, medical consultations, prescriptions and accesses to emergency department were taken into account in the analysis. The direct medical costs due to RV diarrhoea and the costs of vaccination campaign were considered as the main outcome measures in the study.

resultsThe adoption of universal rotavirus vaccination campaign for five years in the LHU 11 Empoli would result in relevant savings due to the health cares avoided. These savings would overlapped the costs of vaccination yet from the second year after the introduction of vaccination. The saving for the Health Service would be 1.5 million Euro after five years of campaign.

conclusionsUniversal vaccination against rotavirus results clinically and economically favourable for both the Health Service and the Society perspectives.

Indexed as

Budget impactRotavirusVaccination

Identifiers

PMID26789991

PMCPMC4718349

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC-ND

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.