Evidence map›Paper›PMID 26789845›Full record

ReviewExpert review of respiratory medicine2016

Asthma and chronic obstructive pulmonary disease overlap syndrome (ACOS): structured literature review and physician insights.

B Ding, A Enstone

Abstract readReview
In one paragraph

Review in Expert review of respiratory medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
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  9. Review
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  12. A Belgian survey on the diagnosis of asthma-COPD overlap syndrome.International journal of chronic obstructive pulmonary disease · 2017
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

B Dinga AstraZeneca R&D Gothenburg , Molndal , Sweden.
A Enstoneb Adelphi Values Ltd , Bollington , UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo understand the key characteristics of Asthma and Chronic Obstructive Pulmonary Disease Overlap Syndrome (ACOS) and to identify evidence gaps relating to the identification, treatment and management of ACOS patients.

methodsA structured literature review and 1-hour telephone interviews with specialist respiratory physicians were conducted (n=10; China, France, Germany, Japan and the USA).

resultsAll 10 physicians used the term ACOS in clinical practice. ACOS was not clearly defined in the literature. Prevalence of ACOS among adult patients with COPD or asthma ranged from 12-55%. ACOS patients had severe disease, with increased exacerbations and hospitalisations compared to some asthma and COPD patients. ACOS represented a clinical challenge due to a lack of evidence-based guidelines distinguishing between asthma, COPD and ACOS. Published data quantifying ACOS costs were limited.

conclusionsThere is a need for consensus evidence-based guidance to facilitate earlier diagnosis and to optimise the management of ACOS patients.

Indexed as

AsthmaPulmonary Disease, Chronic ObstructiveAsiaDiagnosis, DifferentialDisease ProgressionEuropeHealth Care SurveysHospitalizationHumansIncidenceInterviews as TopicLungPredictive Value of TestsPrevalencePrognosisSeverity of Illness IndexACOSAsthmaAsthma and Chronic Obstructive Pulmonary Disease Overlap SyndromeburdenChronic Obstructive Pulmonary DiseaseCOPDhealth-related quality of life

Identifiers

PMID26789845
PMCPMC4819878

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.