ArticlePloS one2016
Economic Impact of a New Rapid PCR Assay for Detecting Influenza Virus in an Emergency Department and Hospitalized Patients.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04048369 (Impact Study of a Rapid Diagnosis of Influenza in the Emergency Medical Service During the 2018-2019 Epidemic Season), which is not on this map. Cited by 28 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Impact Study of a Rapid Diagnosis of Influenza in the Emergency Medical Service During the 2018-2019 Epidemic Season
Who cites it
28 citing papers in PubMed, 3 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- The economic burden of influenza among adults aged 18 to 64: A systematic literature review.Influenza and other respiratory viruses · 2022Pooled it
- Practical Guidance for Clinical Microbiology Laboratories: Viruses Causing Acute Respiratory Tract Infections.Clinical microbiology reviews · 2019Guideline
- Systematic review of the impact of point-of-care testing for influenza on the outcomes of patients with acute respiratory tract infection.Reviews in medical virology · 2018Pooled it
- Point-Of-Care Respiratory Diagnosis and Antibiotic Utilization in the Emergency Department: A Prospective Evaluation of Multiplex PCR.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2026Article
- Accurate detection of influenza A virus by use of a novel cross-priming isothermal amplification-based point-of-care assay.Microbiology spectrum · 2024Article
- Excess hospitalizations and mortality associated with seasonal influenza in Spain, 2008-2018.BMC infectious diseases · 2023Article
- Clinical and economic burden of physician-diagnosed influenza in adults during the 2017/2018 epidemic season in Spain.BMC public health · 2022Article
- Cost-Effectiveness Analysis of Rapid Test Compared to Polymerase Chain Reaction (PCR) in Patients with Acute Respiratory Syndrome.Medical journal of the Islamic Republic of Iran · 2022Article
- Reducing Antibiotic Use in Ambulatory Care Through Influenza Vaccination.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020Article
- Molecular Testing for Acute Respiratory Tract Infections: Clinical and Diagnostic Recommendations From the IDSA's Diagnostics Committee.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020Article
- Impact of a 24/7 Rapid Molecular Assay for Influenza Detection on the Prescription of Oseltamivir.Open forum infectious diseases · 2020Article
- Point of care testing of Influenza A/B and RSV in an adult respiratory assessment unit is associated with improvement in isolation practices and reduction in hospital length of stay.Journal of medical microbiology · 2020Article
- Severe flu management: a point of view.Intensive care medicine · 2020Review
- Article
- Economic and operational impact of an improved pathway using rapid molecular diagnostic testing for patients with influenza-like illness in a German emergency department.Journal of clinical monitoring and computing · 2019Article
- Delayed Diagnosis of Respiratory Syncytial Virus Infections in Hospitalized Adults: Individual Patient Data, Record Review Analysis and Physician Survey in the United States.The Journal of infectious diseases · 2019Article
- Impact of molecular point-of-care testing on clinical management and in-hospital costs of patients suspected of influenza or RSV infection: a modeling study.Journal of medical virology · 2019Article
- The impact of rapid molecular diagnostic testing for respiratory viruses on outcomes for emergency department patients.The Medical journal of Australia · 2019Article
- Impact of Rapid Molecular Detection of Respiratory Viruses on Clinical Outcomes and Patient Management.Journal of clinical microbiology · 2019Article
- Impact of Rapid Molecular Diagnostic Testing of Respiratory Viruses on Outcomes of Adults Hospitalized with Respiratory Illness: a Multicenter Quasi-experimental Study.Journal of clinical microbiology · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Seasonal influenza causes significant morbidity and mortality and has a substantial economic impact on the healthcare system. The main objective of this study was to compare the cost per patient for a rapid commercial PCR assay (Xpert® Flu) with an in-house real-time PCR test for detecting influenza virus. Community patients with influenza like-illness attending the Emergency Department (ED) as well as hospitalized patients in the Hospital Clínic of Barcelona were included. Costs were evaluated from the perspective of the hospital considering the use of resources directly related to influenza testing and treatment. For the purpose of this study, 366 and 691 patients were tested in 2013 and 2014, respectively. The Xpert® Flu test reduced the mean waiting time for patients in the ED by 9.1 hours and decreased the mean isolation time of hospitalized patients by 23.7 hours. This was associated with a 103€ (or about $113) reduction in the cost per patient tested in the ED and 64€ ($70) per hospitalized patient. Sensitivity analyses showed that Xpert® Flu is likely to be cost-saving in hospitals with different contexts and prices.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.