ReviewJournal of preventive medicine and hygiene2015
Epidemiology of Neisseria meningitidis infections: case distribution by age and relevance of carriage.
Review in Journal of preventive medicine and hygiene, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Systematic review of invasive meningococcal disease epidemiology in the Eastern Mediterranean and North Africa region.BMC infectious diseases · 2021Pooled it
- Invasive Meningococcal Disease on the Workplaces: a systematic review.Acta bio-medica : Atenei Parmensis · 2017Pooled it
- Influenza or Meningococcal Immunization During Pregnancy and Mortality in Women and Infants: A Pooled Analysis of Randomized Controlled Trials.The Pediatric infectious disease journal · 2020Trial
- Hyper-diverse antigenic variation and resilience to transmission-reducing intervention in falciparum malaria.Nature communications · 2024Article
- Hyper-diverse antigenic variation and resilience to transmission-reducing intervention in falciparum malaria.medRxiv : the preprint server for health sciences · 2024Article
- Geographical distribution of invasive meningococcal disease and carriage: A spatial analysis.Epidemiology and infection · 2024Article
- Pathogenomic in silico approach identifies NSP-A and Fe-IIISBP as possible drug targets in Neisseria Meningitidis MC58 and development of pharmacophores as novel therapeutic candidates.Molecular diversity · 2023Article
- Cytokine Storm-Definition, Causes, and Implications.International journal of molecular sciences · 2022Review
- A Decade of Fighting Invasive Meningococcal Disease: A Narrative Review of Clinical and Real-World Experience with the MenACWY-CRM Conjugate Vaccine.Infectious diseases and therapy · 2022Review
- Review
- A Comprehensive Review on the Interplay betweenCells · 2021Review
- The Burden of Invasive Bacterial Disease and the Impact of 10-Valent Pneumococcal Conjugate Vaccine in Children <5 years hospitalized for Meningitis in Lusaka, Zambia, 2010-2019.The Journal of infectious diseases · 2021Article
- Factor H binding protein (fHbp)-mediated differential complement resistance of a serogroup CAccess microbiology · 2021Article
- Multiple Linear Regression Model of Meningococcal Disease in Ukraine: 1992-2015.Computational and mathematical methods in medicine · 2020Article
- Personalized Human Papillomavirus Vaccination for Persistence of Immunity for Cervical Cancer Prevention: A Critical Review With Experts' Opinions.Frontiers in oncology · 2020Review
- Evaluation of strain coverage of the multicomponent meningococcal serogroup B vaccine (4CMenB) administered in infants according to different immunisation schedules.Human vaccines & immunotherapeutics · 2019Article
- Immunogenicity of meningococcal polysaccharide ACWY vaccine in primary immunized or revaccinated adults.Clinical and experimental immunology · 2018Article
- Meningococcemia: rare but life-threatening.BMJ case reports · 2018Article
- Do Tuscan people adhere to meningococcal C vaccination during an emergency campaign?Journal of preventive medicine and hygiene · 2018Article
- Challenges and opportunities for meningococcal vaccination in the developing world.Human vaccines & immunotherapeutics · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Notwithstanding different meningococcal serogroups have changed their distribution and their impact in different age classes over time, N. meningitidis' invasive diseases are a major public health issue worldwide, due to the related complications and severe sequelae. Nowadays, the highest rates of invasive disease are registered in children younger than 1 year of age, with a second lesser peak in adolescents and young adults (15-25 years of age). On the contrary, the prevalence of carriage is low in newborns and in school-age children, and increases during adolescence and young-adult age; then it decreases again in older age. N. meningitidis' infection prevalence has greatly decreased in Europe and North America thanks to the use of conjugate vaccines (MenC and MenACWY) as well as the incidence of invasive disease due to serogroup A in sub-saharian Africa after the introduction of MenAfriVac conjugate vaccine. The great success of conjugate vaccines is related not only to the direct protection from disease but also to the impact on carriage; this latter allows an indirect protection of unimmunized subjects. For these reasons, the implementation of immunization with the new generation vaccines in the age classes most impacted by disease and carriage (first year of life, adolescence and young adulthood) could permit to achieve an extraordinary decrease of the incidence of meningococcal disease.
Indexed as
Identifiers
26788731PMC4755119What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.