Evidence map›Paper›PMID 26788342›Full record

ArticleJournal of clinical movement disorders2015

Repetitive finger movement performance differs among Parkinson's disease, Progressive Supranuclear Palsy, and spinocerebellar ataxia.

Elizabeth L Stegemöller, Jennifer Uzochukwu, Mark D Tillman, Nikolaus R McFarland, S H Subramony, Michael S Okun, Chris J Hass

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical movement disorders, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Observational
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Elizabeth L StegemöllerDepartment of Kinesiology, Iowa State University, 235 Forker, Ames, IA 50011 USA ; Department of Applied Physiology and Kinesiology, University of Florida, Gainesville, USA ; Center for Movement Disorders and Neurorestoration, Department of Neurology, University of Florida, McKnight Brain Institute, Gainesville, USA.
Jennifer UzochukwuDepartment of Kinesiology, Iowa State University, 235 Forker, Ames, IA 50011 USA.
Mark D TillmanDepartment of Applied Physiology and Kinesiology, University of Florida, Gainesville, USA ; Department of Kinesiology and Health Promotion, Troy University, Troy, USA.
Nikolaus R McFarlandCenter for Movement Disorders and Neurorestoration, Department of Neurology, University of Florida, McKnight Brain Institute, Gainesville, USA.
S H SubramonyCenter for Movement Disorders and Neurorestoration, Department of Neurology, University of Florida, McKnight Brain Institute, Gainesville, USA.
Michael S OkunCenter for Movement Disorders and Neurorestoration, Department of Neurology, University of Florida, McKnight Brain Institute, Gainesville, USA.
Chris J HassDepartment of Applied Physiology and Kinesiology, University of Florida, Gainesville, USA ; Center for Movement Disorders and Neurorestoration, Department of Neurology, University of Florida, McKnight Brain Institute, Gainesville, USA.
University of Florida · USAllen Institute for Brain Science · USIowa State University · USTroy University · US

Funding

Using social networks to map and evaluate team science across CTSA hubsUL1TR001427 · NCATS · UNIVERSITY OF FLORIDA · PI MITCHELL, DUANE A. · 2015 to 2024
$37.2M
UF CLINICAL AND TRANSLATIONAL SCIENCE AWARDUL1RR029890 · NCRR · UNIVERSITY OF FLORIDA · PI NELSON, DAVID R · 2009 to 2011
$14.4M
NCATS NIH HHS UL1 TR001427NCRR NIH HHS UL1 RR029890
6 · The paper itself

Abstract

backgroundDifferentiating movement disorders is critical for appropriate treatment, prognosis, and for clinical trials. In clinical trials this is especially important as effects can be diluted by inclusion of inappropriately diagnosed participants. In early disease duration phases, disorders often have overlapping clinical features, such as impairments in repetitive finger movement, making diagnosis challenging. The purpose of this pilot study was to examine and compare repetitive finger movement performance in participants diagnosed with idiopathic Parkinson's disease, Progressive Supranuclear Palsy, and spinocerebellar ataxias.

methodsParticipants completed an unconstrained index finger flexion/extension movement (i.e. finger tap) in time with an incremental acoustic tone. Measures of movement rate, movement amplitude, and coefficient of variation were compared among groups.

resultsSignificant differences between groups were revealed for movement rate at faster tone rates. Participants with Parkinson's disease tended to tap faster than the tone rate while participants with Progressive Supranuclear Palsy and spinocerebellar ataxia tended to tap slower. No significant differences were revealed for movement amplitude, but participants with spinocerebellar ataxia demonstrated greater variance in amplitude than participants with Parkinson's disease.

conclusionQuantitative analysis of repetitive finger movement performance at faster rates may be helpful to differentiate Parkinson's Disease, Progressive Supranuclear Palsy and spinocerebellar ataxia.

Indexed as

Coefficient of variationFinger tappingMovement amplitudeMovement disordersMovement rate

Identifiers

PMID26788342
PMCPMC4711045
OpenAlexW2139333954

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.