Evidence map›Paper›PMID 26788325›Full record

ArticleJournal of intensive care2016

The prognostic value of muscle regional oxygen saturation index in severe community-acquired pneumonia: a prospective observational study.

Laura Claverias, Michael Marí, Judith Marín-Corral, Mónica Magret, Sandra Trefler, María Bodí, Antonio García-España, Juan Carlos Yébenes, Sergi Pascual, Joaquim Gea and 1 more

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In one paragraph

Article in Journal of intensive care, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Laura ClaveriasJoan XXIII University Hospital, Critical Care Department, IISPV/URV, Carrer Dr. Mallafre Guasch 4, 43007, Tarragona, Spain ; Research Unit, Joan XXIII University Hospital, IISPV/URV, Tarragona, Spain.ORCID 0000-0002-7170-3788
Michael MaríJoan XXIII University Hospital, Critical Care Department, IISPV/URV, Carrer Dr. Mallafre Guasch 4, 43007, Tarragona, Spain.
Judith Marín-CorralJoan XXIII University Hospital, Critical Care Department, IISPV/URV, Carrer Dr. Mallafre Guasch 4, 43007, Tarragona, Spain.
Mónica MagretJoan XXIII University Hospital, Critical Care Department, IISPV/URV, Carrer Dr. Mallafre Guasch 4, 43007, Tarragona, Spain.
Sandra TreflerJoan XXIII University Hospital, Critical Care Department, IISPV/URV, Carrer Dr. Mallafre Guasch 4, 43007, Tarragona, Spain ; Research Unit, Joan XXIII University Hospital, IISPV/URV, Tarragona, Spain.
María BodíJoan XXIII University Hospital, Critical Care Department, IISPV/URV, Carrer Dr. Mallafre Guasch 4, 43007, Tarragona, Spain ; Research Unit, Joan XXIII University Hospital, IISPV/URV, Tarragona, Spain.
Antonio García-EspañaResearch Unit, Joan XXIII University Hospital, IISPV/URV, Tarragona, Spain.
Juan Carlos YébenesCritical Care Department, Mataró Hospital, Mataró, Spain.
Sergi PascualCIBER de enfermedades respiratorias (CIBERES), ISC III, Bunyola Palma de Mallorca, Spain ; Parc de Salut Mar, IMIM, Pneumology Department, CEXS, UPF, Barcelona, Spain.
Joaquim GeaCIBER de enfermedades respiratorias (CIBERES), ISC III, Bunyola Palma de Mallorca, Spain ; Parc de Salut Mar, IMIM, Pneumology Department, CEXS, UPF, Barcelona, Spain.
Alejandro RodríguezJoan XXIII University Hospital, Critical Care Department, IISPV/URV, Carrer Dr. Mallafre Guasch 4, 43007, Tarragona, Spain ; Research Unit, Joan XXIII University Hospital, IISPV/URV, Tarragona, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCommunity-acquired pneumonia (CAP) mortality exceeds 20 % in critical care patients despite appropriate antibiotic therapy. Regional tissue oxygen saturation index (rSO2) measured with near-infrared spectroscopy (NIRS) might facilitate early detection for patients at risk of serious complications. Our objectives were to determine the relationship between early determination of rSO2 and mortality and to compare discrimination power for mortality of rSO2 and other resuscitation variables in critically ill CAP patients.

methodsThis is a prospective observational study. Patients with CAP were enrolled within 6 h to intensive care admission. Demographics and clinical variables were recorded. rSO2 was determined using NIRS in brachioradialis muscle. All variables were determined at baseline and 24 h after admission.

resultsForty patients were enrolled. Fourteen patients (35 %) had a baseline rSO2 < 60 % and 7 of them died (50 %). Only 1 of 26 (3.8 %) patients with rSO2 ≥ 60 % died (p = 0.007). The area under ROC curve (AUROC) showed consistent mortality discrimination at baseline (0.84, p = 0.03) and at 24 h (0.86, p = 0.006) for rSO2 values. Cox regression analysis showed that "low" rSO2 at ICU admission (hazard ratio (HR) = 8.99; 95 % confidence interval (CI) 1.05-76.8; p = 0.045) and "low" rSO2 at 24 h (HR = 13.18; 95 % CI 1.52-113.6; p = 0.019) were variables independently associated with mortality. In contrast, other variables such as Acute Physiology and Chronic Health Evaluation (APACHE II) score (HR = 1.09; 95 % CI 0.99-1.19; p = 0.052) were not associated with mortality.

conclusionsOur findings suggest that forearm skeletal muscle rSO2 differs in patients with severe CAP according to outcome and might be an early prognosis tool.

Indexed as

Community-acquired pneumoniaMicrocirculationNear-infrared spectroscopySepsisSeptic shock

Identifiers

PMID26788325
PMCPMC4717666

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.