ArticleMolecular autism2016
Olfactory processing in adults with autism spectrum disorders.
Article in Molecular autism, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 54 citations in OpenAlex.
- Exploring Social Biomarkers in High-Functioning Adults with Autism and Asperger's Versus Healthy Controls: A Cross-Sectional Analysis.Journal of autism and developmental disorders · 2020Trial
- A Single Dose, Randomized, Controlled Proof-Of-Mechanism Study of a Novel Vasopressin 1a Receptor Antagonist (RG7713) in High-Functioning Adults with Autism Spectrum Disorder.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2017Trial
- Olfactory Valence-Processing Deficits and Aberrant Brain Network Connectivity Underlie Social Dysfunction in Shank3Neuroscience bulletin · 2026Article
- Atypical Olfactory Identification, Memory and Metacognition in Children With Autism Spectrum Disorder.Journal of autism and developmental disorders · 2026Article
- Odor Experience Stabilizes Glomerular Output Representations in Two Mouse Models of Autism.eNeuro · 2025Article
- Essential Role of the Anterior Piriform Cortex in Mediating Social Novelty Output via a Top-Down Circuit.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Using Tangible User Interfaces (TUIs): Preliminary Evidence on Memory and Comprehension Skills in Children with Autism Spectrum Disorder.Behavioral sciences (Basel, Switzerland) · 2025Article
- Validation of the German Glasgow Sensory Questionnaire in autistic adults.BMC psychiatry · 2025Article
- Giftedness and atypical sexual differentiation: enhanced perceptual functioning through estrogen deficiency instead of androgen excess.Frontiers in endocrinology · 2024Review
- Disgust Processing and Potential Relationships with Behaviors in Autism.Current psychiatry reports · 2023Review
- Robust odor identification in novel olfactory environments in mice.Nature communications · 2023Article
- Amelioration of Maternal Immune Activation-Induced Autism Relevant Behaviors by Gut CommensalInternational journal of molecular sciences · 2022Article
- Juvenile handling rescues autism-related effects of prenatal exposure to valproic acid.Scientific reports · 2022Article
- Endocannabinoid-mediated neuromodulation in the main olfactory bulb at the interface of environmental stimuli and central neural processing.The European journal of neuroscience · 2022Review
- Exposure to GABAFrontiers in psychiatry · 2022Article
- Repeated exposure to kairomone-containing coffee odor improves abnormal olfactory behaviors in heterozygous oxytocin receptor knock-in mice.Frontiers in behavioral neuroscience · 2022Article
- Sensory Processing in the Autism Spectrum: The Role of Attention to Detail and Somatic Trait Anxiety in the Olfactory Perception of the General Population.Journal of autism and developmental disorders · 2021Article
- The Olfactory System as Marker of Neurodegeneration in Aging, Neurological and Neuropsychiatric Disorders.International journal of environmental research and public health · 2021Review
- Characterizing Olfactory Function in Children with Autism Spectrum Disorder and Children with Sensory Processing Dysfunction.Brain sciences · 2020Article
- Prefrontal Responses to Odors in Individuals With Autism Spectrum Disorders: Functional NIRS Measurement Combined With a Fragrance Pulse Ejection System.Frontiers in human neuroscience · 2020Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAs evidenced in the DSM-V, autism spectrum disorders (ASD) are often characterized by atypical sensory behavior (hyper- or hypo-reactivity), but very few studies have evaluated olfactory abilities in individuals with ASD.
methodsFifteen adults with ASD and 15 typically developing participants underwent olfactory tests focused on superficial (suprathreshold detection task), perceptual (intensity and pleasantness judgment tasks), and semantic (identification task) odor processing.
resultsIn terms of suprathreshold detection performance, decreased discrimination scores and increased bias scores were observed in the ASD group. Furthermore, the participants with ASD exhibited increased intensity judgment scores and impaired scores for pleasantness judgments of unpleasant odorants. Decreased identification performance was also observed in the participants with ASD compared with the typically developing participants. This decrease was partly attributed to a higher number of near misses (a category close to veridical labels) among the participants with ASD than was observed among the typically developing participants.
conclusionsThe changes in discrimination and bias scores were the result of a high number of false alarms among the participants with ASD, which suggests the adoption of a liberal attitude in their responses. Atypical intensity and pleasantness ratings were associated with hyperresponsiveness and flattened emotional reactions, respectively, which are typical of participants with ASD. The high number of near misses as non-veridical labels suggested that categorical processing is functional in individuals with ASD and could be explained by attention-deficit/hyperactivity disorder. These findings are discussed in terms of dysfunction of the olfactory system.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.