Evidence map›Paper›PMID 26788280›Full record

ArticleRare tumors2015

T-Cell/Histiocyte-Rich Large B-Cell Lymphoma Presenting as a Primary Central Nervous System Lymphoma.

Pooja Advani, Jason Starr, Abhisek Swaika, Liuyan Jiang, Yushi Qiu, Zhimin Li, Han W Tun

Open access · goldAbstract readCase Reports
In one paragraph

Article in Rare tumors, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Pooja AdvaniDivision of Hematology and Oncology, Department of Internal Medicine, Mayo Clinic , Jacksonville, FL, USA.
Jason StarrDivision of Hematology and Oncology, Department of Internal Medicine, Mayo Clinic, Jacksonville, FL, USA; Cancer Specialists of North Florida, Jacksonville, FL, USA.
Abhisek SwaikaDivision of Hematology and Oncology, Department of Internal Medicine, Mayo Clinic , Jacksonville, FL, USA.
Liuyan JiangDepartment of Laboratory Medicine and Pathology, Mayo Clinic , Jacksonville, FL, USA.
Yushi QiuDepartment of Cancer Biology, Mayo Clinic , Jacksonville, FL, USA.
Zhimin LiDepartment of Cancer Biology, Mayo Clinic , Jacksonville, FL, USA.
Han W TunDivision of Hematology and Oncology, Department of Internal Medicine, Mayo Clinic, Jacksonville, FL, USA; Department of Cancer Biology, Mayo Clinic, Jacksonville, FL, USA.
Mayo Clinic in Florida · USWinnMed · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary central nervous system (PCNSL) lymphoma is an aggressive extranodal non-Hodgkin lymphoma, and most cases are classified as diffuse large B-cell lymphoma (DLBCL) by histology. T-cell/histiocyte-rich large B-cell lymphoma (TCRLBCL) represents a distinct subtype of diffuse large B-cell lymphoma and is characterized by the presence of scattered large neoplastic B-cells in a background of abundant T-cells and histiocytes. This is in contrast to the dense perivascular cuffing of neoplastic B-cells in classic DLBCL. T-cell/histiocyte-rich large B-cell lymphoma should be considered in PCNSL cases in which neoplastic B-cells are sparse and scattered. Immunohistochemistry will help identify the B-cells and surrounding infiltrate rich in Tlymphocytes and histiocytes. Future studies exploring the biology of TCRLBCL and the crosstalk between the neoplastic cells and the surrounding inflammatory infiltrate may provide exciting prospects for future therapies for TCRLBCL.

Indexed as

Central nervous systemdiffuse large B-cell lymphomaosteopontinT-cell/histiocyte-rich large B-cell lymphoma

Identifiers

PMID26788280
PMCPMC4703926
OpenAlexW2215173712

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.