ReviewWorld journal of gastrointestinal endoscopy2016
Bowel cleansing before colonoscopy: Balancing efficacy, safety, cost and patient tolerance.
Review in World journal of gastrointestinal endoscopy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03410524 (Simethicone Pretreatment With Low-volume Polyethylene Glycol-3350 and Bisacodyl in an Effort to Improve Bowel Wall Visualization During Colonoscopy), which is not on this map. Cited by 26 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Simethicone Pretreatment With Low-volume Polyethylene Glycol-3350 and Bisacodyl in an Effort to Improve Bowel Wall Visualization During Colonoscopy
Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 52 citations in OpenAlex.
- Deaths and cardiopulmonary events following colorectal cancer screening-A systematic review with meta-analyses.PloS one · 2024Pooled it
- A meta-analysis of randomized controlled trials of the addition of lubiprostone to bowel preparation before colonoscopy.Medicine · 2020Pooled it
- Mobile app-based bowel preparation training: effects on compliance, quality, and anxiety in colonoscopy patients-a randomized controlled trial.Surgical endoscopy · 2025Trial
- Can a 1-day clear liquid diet with a split -dose polyethylene glycol overcome conventional practice patterns during the preparation for screening colonoscopy?The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2019Trial
- Trial
- Low-volume bowel preparation provides safe and effective pan-enteric capsule endoscopy in suspected or established Crohn's disease.World journal of gastrointestinal endoscopy · 2026Article
- Endoscopic Salvage of Colonic Obstruction Caused by an Unidentified Fibrous Foreign Body.European journal of case reports in internal medicine · 2026Article
- Assessing the association between drug use and ischaemic colitis: a retrospective pharmacovigilance study using FDA Adverse Event data.BMJ open · 2025Article
- Comparing Low Volume Versus Conventional Volume of Polyethylene Glycol for Bowel Preparation during Colonoscopy: A Randomised Controlled Trial.The Malaysian journal of medical sciences : MJMS · 2023Article
- Pre-colonoscopy special guidance and education on intestinal cleaning and examination in older adult patients with constipation.World journal of gastrointestinal surgery · 2022Article
- Novel multiplex stool-based assay for the detection of early-stage colon cancer in a Chinese population.World journal of gastroenterology · 2022Article
- A multicenter, prospective, inpatient feasibility study to evaluate the use of an intra-colonoscopy cleansing device to optimize colon preparation in hospitalized patients: the REDUCE study.BMC gastroenterology · 2021Article
- Patient experience with NER1006 as a bowel preparation for colonoscopy: a prospective, multicenter US survey.BMC gastroenterology · 2021Article
- Safety and efficacy of sodium picosulfate, magnesium oxide, and citric acid bowel preparation in patients with baseline renal impairment or diabetes: subanalysis of a randomized, controlled trial.Therapeutic advances in gastroenterology · 2021Article
- Triage May Improve Selection to Colonoscopy and Reduce the Number of Unnecessary Colonoscopies.Cancers · 2020Article
- Bowel Preparation for Colonoscopy in 2020: A Look at the Past, Present, and Future.Current gastroenterology reports · 2020Review
- The importance of colonoscopy bowel preparation for the detection of colorectal lesions and colorectal cancer prevention.Endoscopy international open · 2020Review
- Randomized, double-blinded, placebo-controlled trial evaluating simethicone pretreatment with bowel preparation during colonoscopy.World journal of gastrointestinal endoscopy · 2019Article
- Efficacy and safety of a ready-to-drink bowel preparation for colonoscopy: a randomized, controlled, non-inferiority trial.Therapeutic advances in gastroenterology · 2019Article
- A comparative review of use of sulphate and phosphate salts for colonoscopy preparations and their potential for nephrotoxicity.Endoscopy international open · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Effective colorectal cancer screening relies on reliable colonoscopy findings which are themselves dependent on adequate bowel cleansing. Research has consistently demonstrated that inadequate bowel preparation adversely affects the adenoma detection rate and leads gastroenterologists to recommend earlier follow up than is consistent with published guidelines. Poor preparation affects as many as 30% of colonoscopies and contributes to an increased cost of colonoscopies. Patient tolerability is strongly affected by the preparation chosen and manner in which it is administered. Poor tolerability is, in turn, associated with lower quality bowel preparations. Recently, several new developments in both agents being used for bowel preparation and in the timing of administration have brought endoscopists closer to achieving the goal of effective, reliable, safe, and tolerable regimens. Historically, large volume preparations given in a single dose were administered to patients in order to achieve adequate bowel cleansing. These were poorly tolerated, and the unpleasant taste of and significant side effects produced by these large volume regimens contributed significantly to patients' inability to reliably complete the preparation and to a reluctance to repeat the procedure. Smaller volumes, including preparations that are administered as tablets to be consumed with water, given as split doses have significantly improved both the patient experience and efficacy, and an appreciation of the importance of the preparation to colonoscopy interval have produced additional cleansing.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.