ReviewTherapeutic advances in neurological disorders2016
The optimal management of headaches in children and adolescents.
Review in Therapeutic advances in neurological disorders, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.
- Drug interventions for acute treatment of pediatric migraine: a systematic review and network meta-analysis.Frontiers in pharmacology · 2026Pooled it
- Hospitalized primary headache in children after emergency department evaluation: a retrospective cohort study.Acta neurologica Belgica · 2026Article
- Multidisciplinary management of headache in developmental age: effects on school performance, quality of life, and therapeutic perspectives.Naunyn-Schmiedeberg's archives of pharmacology · 2026Review
- Les troubles à symptomatologie somatique et apparentés: directives d'évaluation et de prise en charge pour les professionnels de la santé des enfants.Paediatrics & child health · 2025Review
- Somatic symptom and related disorders: Guidance on assessment and management for paediatric health care providers.Paediatrics & child health · 2025Review
- Developmental trends in headache: an Italian school-based study of age- and gender-related changes in clinical characteristics and burden from childhood to adolescence.Therapeutic advances in neurological disorders · 2025Article
- Article
- Pediatric Headache in Primary Care and Emergency Departments: Consensus with RAND/UCLA Method.Life (Basel, Switzerland) · 2022Article
- A Comparative Study on the Efficacy of Coenzyme Q10 and Amitriptyline in the Prophylactic Treatment of Migraine Headaches in Children: A Randomized Controlled Trial.Advanced biomedical research · 2022Article
- Management of Chronic Migraine in Children and Adolescents: Where are We in 2022?Pediatric health, medicine and therapeutics · 2022Review
- Transnasal Sphenopalatine Ganglion Block for the Preventive Treatment of Chronic Daily Headache in Adolescents.Children (Basel, Switzerland) · 2021Article
- Migraine and Mood in Children.Behavioral sciences (Basel, Switzerland) · 2021Review
- Drug Treatment of Epilepsy Neuropsychiatric Comorbidities in Children.Paediatric drugs · 2021Review
- Intravenous Migraine Treatment in Children and Adolescents.Current pain and headache reports · 2020Review
- Hsa-miR-34a-5p and hsa-miR-375 as Biomarkers for Monitoring the Effects of Drug Treatment for Migraine Pain in Children and Adolescents: A Pilot Study.Journal of clinical medicine · 2019Article
- An observational study of fixed-dose Tanacetum parthenium nutraceutical preparation for prophylaxis of pediatric headache.Italian journal of pediatrics · 2019Observational
- A Possible Pathogenic Linkage Among Headache, Migraine, and Nocturnal Enuresis in Children.International neurourology journal · 2016Article
- Resolution of Refractory Headache Symptoms Following Cervical Spinal Manipulation and Electrical Dry Needling in an Adolescent Female: A Case Report.Sage open pediatricsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The recognition of the diagnosis of migraine in children is increasing. Early and aggressive treatment of migraine in this population with the use of over-the-counter medications has proven effective. The off-label use of many migraine-specific medications is often accepted in the absence of sufficient evidenced-based trials. Mild to severe cases of migraine should be treated with nonsteroidal anti-inflammatory drugs, with triptans used in moderate to severe headaches unresponsive to over-the-counter therapy. Rescue medication including dihydroergotamine [DHE] should be used for status migrainosus, preferably in the hospital setting. Antiemetics that have antidopaminergic properties can be helpful in patients with associated symptoms of nausea and vomiting through their action on central migraine generation. Furthermore, patients and families should be educated on nonpharmacologic management such as lifestyle modification and avoidance of triggers that can prevent episodic migraine.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.