Evidence map›Paper›PMID 26788065›Full record

ReviewStem cells international2016

The Controversy, Challenges, and Potential Benefits of Putative Female Germline Stem Cells Research in Mammals.

Zezheng Pan, Mengli Sun, Xia Liang, Jia Li, Fangyue Zhou, Zhisheng Zhong, Yuehui Zheng

Registry-linked trialAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Stem cells international, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03621683 (Antioxidants vs.Ovarian Bio-stimulation Therapy to Rescue the Ovarian Reserve), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03621683 nacompletednot on this map

Antioxidants vs.Ovarian Bio-stimulation Therapy to Rescue the Ovarian Reserve

TypeinterventionalSponsorLucy ColemanRan2016 to 2017Enrolled78ConditionsOvarian ReserveArmsblood rich plasma platelets, Antioxidant therapy
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Comparison of RNA mMolecular therapy. Nucleic acids · 2021
    Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zezheng PanMedical Teaching Laboratory Center, Jiangxi Medical College, Nanchang University, Nanchang 330031, China; Faculty of Basic Medical Science, Jiangxi Medical College, Nanchang University, Nanchang 330031, China.
Mengli SunMedical Teaching Laboratory Center, Jiangxi Medical College, Nanchang University, Nanchang 330031, China; College of Life Science, Chinese PLA General Hospital, Beijing 100039, China.
Xia LiangMedical Teaching Laboratory Center, Jiangxi Medical College, Nanchang University, Nanchang 330031, China.
Jia LiMedical Teaching Laboratory Center, Jiangxi Medical College, Nanchang University, Nanchang 330031, China.
Fangyue ZhouMedical Teaching Laboratory Center, Jiangxi Medical College, Nanchang University, Nanchang 330031, China.
Zhisheng ZhongThe Second Affiliated Hospital of Nanchang University, Nanchang University, Nanchang 330006, China.
Yuehui ZhengMedical Teaching Laboratory Center, Jiangxi Medical College, Nanchang University, Nanchang 330031, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The conventional view is that female mammals lose their ability to generate new germ cells after birth. However, in recent years, researchers have successfully isolated and cultured a type of germ cell from postnatal ovaries in a variety of mammalian species that have the abilities of self-proliferation and differentiation into oocytes, and this finding indicates that putative germline stem cells maybe exist in the postnatal mammalian ovaries. Herein, we review the research history and discovery of putative female germline stem cells, the concept that putative germline stem cells exist in the postnatal mammalian ovary, and the research progress, challenge, and application of putative germline stem cells in recent years.

Identifiers

PMID26788065
PMCPMC4693009

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.