Observational studyBritish journal of anaesthesia2016
Intraoperative transfusion practices in Europe.
Observational study in British journal of anaesthesia, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 5 registered trials, which are not on this map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
European Transfusion Practice and Outcome Study A Multi-central Evaluation of Standard of Transfusion Care and Clinical Outcome for Elective Surgical Patients. Observational Study.
Restrictive Versus Liberal Transfusion for Elective Major Surgery and Perioperative Outcomes: Mortality, Morbidity and Requirement of Postoperative Blood Transfusion
Investigation of the Transfusion Practices in Surgical Patients in Turkey
Fluid Day: Observational Study About Fluid Therapy Administered in Adult Patients Undergoing Surgery in Our Country
Effect of Perioperative Transfusion on Early and Late Outcome After Major Elective Surgery
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Transfusion strategies in non-bleeding critically ill adults: a clinical practice guideline from the European Society of Intensive Care Medicine.Intensive care medicine · 2020Guideline
- Machine learning-based prediction of transfusion.Transfusion · 2020Trial
- Marginal anaemia and perioperative transfusion in female patients undergoing cardiac surgery.Vox sanguinis · 2026Article
- Complication rates following open surgical removal of osteosynthesis material from the pelvis and acetabulum: a retrospective case series of 154 removals.Acta orthopaedica · 2026Article
- Integrating Peripheral Nerve Blocks in Multiple Trauma Care: Current Evidence and Clinical Challenges.Journal of clinical medicine · 2025Review
- Physiologic transfusion thresholds, better than using Hb-based thresholds?Blood transfusion = Trasfusione del sangue · 2025Article
- Development and validation of machine learning models for intraoperative blood transfusion prediction in severe lumbar disc herniation.iScience · 2024Article
- Patient Blood Management in Microsurgical Procedures for Reconstructive Surgery.Diagnostics (Basel, Switzerland) · 2023Article
- The Limits of Acute Anemia.Journal of clinical medicine · 2022Review
- Predicting organ functioning with and without blood transfusion in critically ill patients with anemia.Transfusion · 2022Article
- RBC Transfusion Triggers: Is There Anything New?Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2020Review
- Peri-operative blood transfusion in elective major surgery: incidence, indications and outcome - an observational multicentre study.Blood transfusion = Trasfusione del sangue · 2020Observational
- Evaluation for Perioperative Blood Transfusion during Major Abdominal Procedures in a Pediatric Population: A Retrospective Observation Cohort Study.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2020Article
- Surgical prescription of epoetin alfa in contemporary total hip arthroplasty: a prospective comparative study.International orthopaedics · 2020Article
- Sublingual microcirculation does not reflect red blood cell transfusion thresholds in the intensive care unit-a prospective observational study in the intensive care unit.Critical care (London, England) · 2020Observational
- Guidelines on the intraoperative transfusion of red blood cells: a protocol for systematic review.BMJ open · 2019Article
- Influence of factor XIII activity on post-operative transfusion in congenital cardiac surgery-A retrospective analysis.PloS one · 2018Article
- Administration Safety of Blood Products - Lessons Learned from a National Registry for Transfusion and Hemotherapy Practice.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2017Article
- Hemoglobin concentrations and RBC transfusion thresholds in patients with acute brain injury: an international survey.Critical care (London, England) · 2017Article
- Development of Multivariable Models to Predict and Benchmark Transfusion in Elective Surgery Supporting Patient Blood Management.Applied clinical informatics · 2017Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTransfusion of allogeneic blood influences outcome after surgery. Despite widespread availability of transfusion guidelines, transfusion practices might vary among physicians, departments, hospitals and countries. Our aim was to determine the amount of packed red blood cells (pRBC) and blood products transfused intraoperatively, and to describe factors determining transfusion throughout Europe.
methodsWe did a prospective observational cohort study enrolling 5803 patients in 126 European centres that received at least one pRBC unit intraoperatively, during a continuous three month period in 2013.
resultsThe overall intraoperative transfusion rate was 1.8%; 59% of transfusions were at least partially initiated as a result of a physiological transfusion trigger- mostly because of hypotension (55.4%) and/or tachycardia (30.7%). Haemoglobin (Hb)- based transfusion trigger alone initiated only 8.5% of transfusions. The Hb concentration [mean (sd)] just before transfusion was 8.1 (1.7) g dl(-1) and increased to 9.8 (1.8) g dl(-1) after transfusion. The mean number of intraoperatively transfused pRBC units was 2.5 (2.7) units (median 2).
conclusionAlthough European Society of Anaesthesiology transfusion guidelines are moderately implemented in Europe with respect to Hb threshold for transfusion (7-9 g dl(-1)), there is still an urgent need for further educational efforts that focus on the number of pRBC units to be transfused at this threshold. CLINICAL
trial registrationNCT 01604083.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.