ArticleLearning & memory (Cold Spring Harbor, N.Y.)2016
Optimization of visual training for full recovery from severe amblyopia in adults.
Article in Learning & memory (Cold Spring Harbor, N.Y.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 31 citations in OpenAlex.
- Impact of transcranial Direct Current Stimulation on stereoscopic vision and retinal structure in adult amblyopic rodents.Eye and brain · 2024Article
- Psychedelics and Neural Plasticity: Therapeutic Implications.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Article
- Chronic Monocular Deprivation Reveals MMP9-Dependent and -Independent Aspects of Murine Visual System Plasticity.International journal of molecular sciences · 2022Article
- Rehabilitation of visual perception in cortical blindness.Handbook of clinical neurology · 2022Review
- Article
- 17α Estradiol promotes plasticity of spared inputs in the adult amblyopic visual cortex.Scientific reports · 2019Article
- Neuregulin directed molecular mechanisms of visual cortical plasticity.The Journal of comparative neurology · 2019Review
- Modification of Peak Plasticity Induced by Brief Dark Exposure.Neural plasticity · 2019Article
- Enhanced visual experience rehabilitates the injured brain in Xenopus tadpoles in an NMDAR-dependent manner.Journal of neurophysiology · 2019Article
- Amblyopia: New molecular/pharmacological and environmental approaches.Visual neuroscience · 2018Review
- Critical periods in amblyopia.Visual neuroscience · 2018Review
- The development of human visual cortex and clinical implications.Eye and brain · 2018Review
- Article
- Peripheral Sensory Deprivation Restores Critical-Period-like Plasticity to Adult Somatosensory Thalamocortical Inputs.Cell reports · 2017Article
- Neuregulin-Dependent Regulation of Fast-Spiking Interneuron Excitability Controls the Timing of the Critical Period.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
The severe amblyopia induced by chronic monocular deprivation is highly resistant to reversal in adulthood. Here we use a rodent model to show that recovery from deprivation amblyopia can be achieved in adults by a two-step sequence, involving enhancement of synaptic plasticity in the visual cortex by dark exposure followed immediately by visual training. The perceptual learning induced by visual training contributes to the recovery of vision and can be optimized to drive full recovery of visual acuity in severely amblyopic adults.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.