ReviewBurns : journal of the International Society for Burn Injuries2016
Current concepts on burn wound conversion-A review of recent advances in understanding the secondary progressions of burns.
Review in Burns : journal of the International Society for Burn Injuries, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
45 citing papers in PubMed, 119 citations in OpenAlex.
- Experimental Burn Induction in Laboratory Animals: A Scoping Review of Methods, Reproducibility, Operator-Dependent Variability, and Relevance to Soft Tissue Reconstruction and Repair.Bioengineering (Basel, Switzerland) · 2026Review
- PLA/BC/lard nanofiber composites as next-generation burn wound dressings.RSC advances · 2026Article
- Burn Selection: How Fire Injury Shaped Human Evolution.BioEssays : news and reviews in molecular, cellular and developmental biology · 2026Review
- Sulfated Polysaccharides in Wound Healing: From Bioactive Materials Design to Regenerative Therapeutics.International journal of nanomedicine · 2026Review
- Burn Progression in Human Skin-A Review of Current Knowledge and Opportunities for Future Research.Journal of burn care & research : official publication of the American Burn Association · 2025Review
- Burn Wound Dynamics Measured with Hyperspectral Imaging.European burn journal · 2025Article
- Coagulation depth estimation using a line scanner for depth-resolved laser speckle contrast imaging.Biomedical optics express · 2024Article
- Mechanisms of action behind the protective effects of proactive esophageal cooling during radiofrequency catheter ablation in the left atrium.Heart rhythm O2 · 2024Review
- Tranexamic acid reduces inflammation, edema and burn wound conversion in a rodent model.Burns : journal of the International Society for Burn Injuries · 2024Article
- [Expert consensus on the treatment of second-degree burn wounds (2024 edition)Ⅰ: pre-hospital first aid and non-surgical treatment].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2024Article
- Consensus on the treatment of second-degree burn wounds (2024 edition).Burns & trauma · 2024Article
- Tunable Sulfated Alginate-based Hydrogel Platform with enhanced anti-inflammatory and antioxidant capacity for promoting burn wound repair.Journal of nanobiotechnology · 2023Article
- Alginate and Nanocellulose Dressings With Extract From Salmon Roe Reduce Inflammation and Accelerate Healing of Porcine Burn Wounds.Journal of burn care & research : official publication of the American Burn Association · 2023Article
- [Mechanism and prevention and treatment strategy of progressive injury in high-voltage electric burns].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2023Article
- Role of medicinal herbs and phytochemicals in post burn management.Inflammopharmacology · 2023Review
- Flir OneAnnals of burns and fire disasters · 2023Article
- Predictor of Burn Wound Conversion as a Reference for Conservative and Operative Management: Review of Imagej, Flir OneAnnals of burns and fire disasters · 2023Article
- Review
- Review
- Molecular imbalance mechanism of skin and blood leucocytes in severe burn patients at different burn times.Annals of translational medicine · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
Burn wound conversion describes the process by which superficial partial thickness burns convert into deeper burns necessitating surgical intervention. Fully understanding and thus controlling this phenomenon continues to defy burn surgeons. However, potentially guiding burn wound progression so as to obviate the need for surgery while still bringing about healing with limited scarring is the major unmet challenge. Comprehending the pathophysiologic background contributing to deeper progression of these burns is an essential prerequisite to planning any intervention. In this study, a review of articles examining burn wound progression over the last five years was conducted to analyze trends in recent burn progression research, determine changes in understanding of the pathogenesis of burn conversion, and subsequently examine the direction for future research in developing therapies. The majority of recent research focuses on applying therapies from other disease processes to common underlying pathogenic mechanisms in burn conversion. While ischemia, inflammation, and free oxygen radicals continue to demonstrate a critical role in secondary necrosis, novel mechanisms such as autophagy have also been shown to contribute affect significantly burn progression significantly. Further research will have to determine whether multiple mechanisms should be targeted when developing clinical therapies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.