ArticleScientific reports2016
A sex-inducing pheromone triggers cell cycle arrest and mate attraction in the diatom Seminavis robusta.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 76 citations in OpenAlex.
- Some Bioactive Natural Products from Diatoms: Structures, Biosyntheses, Biological Roles, and Properties: 2015-2025.Marine drugs · 2026Review
- Recent Advances in Understanding the Sex Pheromone-Mediated Communication of Diatoms.ChemPlusChem · 2025Review
- Sexual reproduction during diatom bloom.ISME communications · 2025Article
- Algal blooms in the ocean: hot spots for chemically mediated microbial interactions.Nature reviews. Microbiology · 2024Review
- What Was Old Is New Again: The Pennate DiatomMarine drugs · 2022Review
- Crystal structure of the pheromone Er-13 from the ciliate Euplotes raikovi, with implications for a protein-protein association model in pheromone/receptor interactions.Journal of structural biology · 2022Article
- Trade-off between sex and growth in diatoms: Molecular mechanisms and demographic implications.Science advances · 2022Article
- Light intensity and spectral composition drive reproductive success in the marine benthic diatom Seminavis robusta.Scientific reports · 2021Article
- Asymmetric mating behavior of isogamous budding yeast.Science advances · 2021Article
- Pheromone Mediated Sexual Reproduction of Pennate Diatom Cylindrotheca closterium.Journal of chemical ecology · 2021Article
- Integrative omics identification, evolutionary and structural analysis of low affinity nitrate transporters in diatoms, diNPFs.Open biology · 2021Article
- Mating type specific transcriptomic response to sex inducing pheromone in the pennate diatom Seminavis robusta.The ISME journal · 2021Article
- An optimised method for intact nuclei isolation from diatoms.Scientific reports · 2021Article
- Synchronized emergence under diatom sperm competition.Proceedings. Biological sciences · 2020Article
- The Seminavis robusta genome provides insights into the evolutionary adaptations of benthic diatoms.Nature communications · 2020Article
- A Metabolomics Exploration of the Sexual Phase in the Marine DiatomMarine drugs · 2020Article
- Diatom Molecular Research Comes of Age: Model Species for Studying Phytoplankton Biology and Diversity.The Plant cell · 2020Review
- Cytoplasmic retention and degradation of a mitotic inducer enable plant infection by a pathogenic fungus.eLife · 2019Article
- Article
- Decision-making of the benthic diatom Seminavis robusta searching for inorganic nutrients and pheromones.The ISME journal · 2019Article
Corrections and comments
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Authors and funding
19 authors at 5 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although sexual reproduction is believed to play a major role in the high diversification rates and species richness of diatoms, a mechanistic understanding of diatom life cycle control is virtually lacking. Diatom sexual signalling is controlled by a complex, yet largely unknown, pheromone system. Here, a sex-inducing pheromone (SIP(+)) of the benthic pennate diatom Seminavis robusta was identified by comparative metabolomics, subsequently purified, and physicochemically characterized. Transcriptome analysis revealed that SIP(+) triggers the switch from mitosis-to-meiosis in the opposing mating type, coupled with the transcriptional induction of proline biosynthesis genes, and the release of the proline-derived attraction pheromone. The induction of cell cycle arrest by a pheromone, chemically distinct from the one used to attract the opposite mating type, highlights the existence of a sophisticated mechanism to increase chances of mate finding, while keeping the metabolic losses associated with the release of an attraction pheromone to a minimum.
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