ArticleBMC plant biology2016
OsHKT1;4-mediated Na(+) transport in stems contributes to Na(+) exclusion from leaf blades of rice at the reproductive growth stage upon salt stress.
Article in BMC plant biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.
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75 citing papers in PubMed, 207 citations in OpenAlex.
- Identification of rice DUF1719 gene family and analysis of alkaline tolerance function of OsDUF1719.8.Functional & integrative genomics · 2026Article
- Integrated transcriptomic and metabolomic analysis reveals the salt tolerance mechanisms in Lagerstroemia indica.BMC plant biology · 2026Article
- From Model Plants to Staple Crops: Molecular Mechanisms of Plant Saline-Alkali Tolerance.Plants (Basel, Switzerland) · 2026Review
- Different Substrates Drive Differential Responses of Rice to Salt Stress.Rice (New York, N.Y.) · 2025Article
- Molecular Breeding for Abiotic Stress Tolerance in Crops: Recent Developments and Future Prospectives.International journal of molecular sciences · 2025Review
- OsWNK9 regulates the expression of key transcription factors, phytohormonal, and transporters genes to improve salinity stress tolerance in rice.Scientific reports · 2025Article
- Aptamer‑mediated modulation of eEF1 enhances salt stress tolerance in rice.BMC plant biology · 2025Article
- Genome-wide association mapping for salinity recovery of rice seedlings grown in hydroponic and field conditions.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025Article
- Molecular Alchemy: Converting Stress into Resilience via Secondary Metabolites and Calcium Signaling in Rice.Rice (New York, N.Y.) · 2025Review
- OsPIP2;4 aquaporin water channel primarily expressed in roots of rice mediates both water and nonselective NaScientific reports · 2025Article
- Green biogenic sulfur nanoparticles enhanceFrontiers in plant science · 2025Article
- Overexpression of Abscisic Acid Biosynthesis GenePlants (Basel, Switzerland) · 2024Article
- A high-affinity potassium transporter (MeHKT1) from cassava (Manihot esculenta) negatively regulates the response of transgenic Arabidopsis to salt stress.BMC plant biology · 2024Article
- Research on Physiological Characteristics and Differential Gene Expression of Rice Hybrids and Their Parents under Salt Stress at Seedling Stage.Plants (Basel, Switzerland) · 2024Article
- Strategies for combating plant salinity stress: the potential of plant growth-promoting microorganisms.Frontiers in plant science · 2024Review
- Rice NaFrontiers in plant science · 2024Article
- Type-B response regulator OsRR22 forms a transcriptional activation complex with OsSLR1 to modulate OsHKT2;1 expression in rice.Science China. Life sciences · 2023Article
- The Molecular Mechanism of Potassium Absorption, Transport, and Utilization in Rice.International journal of molecular sciences · 2023Review
- Abiotic Stress in Rice: Visiting the Physiological Response and Its Tolerance Mechanisms.Plants (Basel, Switzerland) · 2023Review
- Jacalin-related lectin 45 (OsJRL45) isolated from 'sea rice 86' enhances rice salt tolerance at the seedling and reproductive stages.BMC plant biology · 2023Article
15 more citing papers are in PubMed but not listed here.
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13 authors at 5 institutions in 3 countries.
Funding
Abstract
backgroundNa(+) exclusion from leaf blades is one of the key mechanisms for glycophytes to cope with salinity stress. Certain class I transporters of the high-affinity K(+) transporter (HKT) family have been demonstrated to mediate leaf blade-Na(+) exclusion upon salinity stress via Na(+)-selective transport. Multiple HKT1 transporters are known to function in rice (Oryza sativa). However, the ion transport function of OsHKT1;4 and its contribution to the Na(+) exclusion mechanism in rice remain to be elucidated.
resultsHere, we report results of the functional characterization of the OsHKT1;4 transporter in rice. OsHKT1;4 mediated robust Na(+) transport in Saccharomyces cerevisiae and Xenopus laevis oocytes. Electrophysiological experiments demonstrated that OsHKT1;4 shows strong Na(+) selectivity among cations tested, including Li(+), Na(+), K(+), Rb(+), Cs(+), and NH4 (+), in oocytes. A chimeric protein, EGFP-OsHKT1;4, was found to be functional in oocytes and targeted to the plasma membrane of rice protoplasts. The level of OsHKT1;4 transcripts was prominent in leaf sheaths throughout the growth stages. Unexpectedly however, we demonstrate here accumulation of OsHKT1;4 transcripts in the stem including internode II and peduncle in the reproductive growth stage. Moreover, phenotypic analysis of OsHKT1;4 RNAi plants in the vegetative growth stage revealed no profound influence on the growth and ion accumulation in comparison with WT plants upon salinity stress. However, imposition of salinity stress on the RNAi plants in the reproductive growth stage caused significant Na(+) overaccumulation in aerial organs, in particular, leaf blades and sheaths. In addition, (22)Na(+) tracer experiments using peduncles of RNAi and WT plants suggested xylem Na(+) unloading by OsHKT1;4.
conclusionsTaken together, our results indicate a newly recognized function of OsHKT1;4 in Na(+) exclusion in stems together with leaf sheaths, thus excluding Na(+) from leaf blades of a japonica rice cultivar in the reproductive growth stage, but the contribution is low when the plants are in the vegetative growth stage.
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